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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (99%), Rat (99%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66569. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene is thought to be part of a large multi-subunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, the encoded protein can bind c-myc promoter-binding protein 1 and block its transcriptional repression capability. Mutations in this gene are a cause of spondyloepiphyseal dysplasia tarda (SEDT). A processed pseudogene of this gene is located on chromosome 19, and other pseudogenes are found on chromosomes 8 and Y. Alternatively spliced transcript variants have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MBP-1-interacting protein 2A; MIP-2A; Sedlin; Trafficking protein particle complex subunit 2; Trafficking protein particle complex subunit 2B
Gene Aliases: hYP38334; MIP2A; SEDL; SEDLP1; SEDT; TRAPPC2; TRAPPC2.19; TRAPPC2B; TRAPPC2P1; TRS20; ZNF547L
UniProt ID: (Human) P0DI81
Entrez Gene ID: (Human) 6399
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