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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (68%), Rat (68%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53647. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
TREML1 is located in a gene cluster on chromosome 6 with the single Ig variable domain activating receptors TREM1 and TREM2, but it has distinct structural and functional properties. TREML1 enhances calcium signaling in an SHP2 -dependent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MGC119173; OTTHUMP00000017858; TLT-1; TREM; Trem-like transcript 1 protein; Triggering receptor expressed on myeloid cells; triggering receptor expressed on myeloid cells-like 1; Triggering receptor expressed on myeloid cells-like protein 1
Gene Aliases: dJ238O23.3; GLTL1825; PRO3438; TLT-1; TLT1; TREML1; UNQ1825/PRO3438
UniProt ID: (Human) Q86YW5
Entrez Gene ID: (Human) 340205
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