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Invitrogen
Human TRIM67 (aa 9-85) Control Fragment Recombinant Protein
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Product Details
RP-94143
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
VCGSLFREPIILPCSHNVCLPCARTIAVQTPDGEQHLPQPLLLSRGSGLQAGAAAAASLEHDAAAGPACGGAGGSAA
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (77%), Rat (77%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-57056. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
The TRIM67 gene encodes a member of the tripartite motif (TRIM) protein family, which is involved in various cellular processes including protein ubiquitination, signal transduction, and immune responses. TRIM67 contains RING, B-box, and coiled-coil domains, characteristic of TRIM proteins, which facilitate interactions with other proteins and contribute to its role in ubiquitination and cellular regulation. TRIM67 is notably expressed in the brain and has been associated with neurodevelopmental processes, particularly influencing neuronal differentiation and synapse formation. This gene plays a regulatory role in signaling pathways that are critical for neural development, and mutations or dysregulation in TRIM67 have been linked to neurodevelopmental disorders and cognitive deficits. Additionally, TRIM67's involvement in protein degradation and signal modulation may impact cellular architecture and brain function. Ongoing research seeks to elucidate TRIM67's precise mechanisms and potential therapeutic targets for neurological conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: TRIM9-like protein; TRIM9-like protein TNL; Tripartite motif-containing protein 67
Gene Aliases: TNL; TRIM67
UniProt ID: (Human) Q6ZTA4
Entrez Gene ID: (Human) 440730
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