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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (79%), Rat (79%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-82835. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene is expressed in many cancer cell lines. Its expression in normal tissues, however, was found to be restricted to prostate. This gene was also found to be differentially expressed in androgen-dependent versus androgen-independent prostate cancer cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: E3 ubiquitin-protein ligase TRIM68; FLJ10369; MGC126176; RING finger protein 137; RING-type E3 ubiquitin transferase TRIM68; Ro/SSA1 related protein; SS-56; SSA protein SS-56; Tripartite motif-containing protein 68
Gene Aliases: GC109; RNF137; SS-56; SS56; TRIM68
UniProt ID: (Human) Q6AZZ1
Entrez Gene ID: (Human) 55128
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