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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-57019. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The enzyme encoded by this gene is an important intermediary in mammalian carbohydrate interconversions. It transfers a glucose moiety from glucose-1-phosphate to MgUTP and forms UDP-glucose and MgPPi. In liver and muscle tissue, UDP-glucose is a direct precursor of glycogen; in lactating mammary gland it is converted to UDP-galactose which is then converted to lactose. The eukaryotic enzyme has no significant sequence similarity to the prokaryotic enzyme. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: testis tissue sperm-binding protein Li 58p; UDP-glucose diphosphorylase; UDP-glucose pyrophosphorylase; UDP-glucose pyrophosphorylase 1; UDPGP; UGPase 2; uridyl diphosphate glucose pyrophosphorylase 2; Uridyl diphosphate glucose pyrophosphorylase-1; UTP--glucose-1-phosphate uridylyltransferase; UTP--glucose-1-phosphate uridylyltransferase 2; UTP-glucose-1-phosphate uridyltransferase
Gene Aliases: pHC379; UDPG; UDPGP; UDPGP2; UGP1; UGP2; UGPP1; UGPP2
UniProt ID: (Human) Q16851
Entrez Gene ID: (Human) 7360
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