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Highest antigen sequence indentity to the following orthologs: Mouse (37%), Rat (37%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53531. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Urotensin II is an active cyclic heptapeptide absolutely conserved from lamprey to human. The active peptide acts as a vasoconstrictor and is expressed only in brain tissue. Despite the gene family name similarity, this gene is not homologous to urocortin, a member of the sauvagine/corticotropin releasing factor/urotensin I family. Most of the proprotein is cleaved to make the mature peptide.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: prepro U-II; U-II; Urotensin II; Urotensin-2
Gene Aliases: PRO1068; U-II; UCN2; UII; UNQ525/PRO1068; UTS2
UniProt ID: (Human) O95399
Entrez Gene ID: (Human) 10911
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