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Invitrogen
Human WRCH1 (aa 165-188) Control Fragment Recombinant Protein
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Product Details
RP-101297
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
LREDVKVLIELDKCKEKPVPEEAA
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-62018. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
This gene encodes a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation. A non-coding transcript variant of this gene results from naturally occurring read-through transcription between this locus and the neighboring DUSP5P (dual specificity phosphatase 5 pseudogene) locus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2310026M05Rik; CDC42-like GTPase 1; GTP-binding protein like 1; GTP-binding protein SB128; GTP-binding protein-like 1; ras homolog gene family, member U; ras-like gene family member U; Rho GTPase-like protein ARHU; Rho-related GTP-binding protein RhoU; RHOU; Ryu GTPase; Wnt-1 responsive Cdc42 homolog 1; WRCH-1
Gene Aliases: ARHU; CDC42L1; G28K; hG28K; RHOU; SB128; WRCH1
UniProt ID: (Human) Q7L0Q8
Entrez Gene ID: (Human) 58480
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