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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (33%), Rat (33%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-82477. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: chemokine (C motif) receptor 1; chemokine (C motif) XC receptor 1; Chemokine XC receptor 1; G protein-coupled receptor 5; G-protein coupled receptor 5; Lymphotactin receptor; XC chemokine receptor 1
Gene Aliases: CCXCR1; GPR5; XCR1
UniProt ID: (Human) P46094
Entrez Gene ID: (Human) 2829
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