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Invitrogen
Human ZGLP1 (aa 94-175) Control Fragment Recombinant Protein
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Product Details
RP-99247
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
LLDRDSKDTQTRISQKGRRLQPPGTPSAPPQRRPRKQLNPCRGTERVDPGFEGVTLKFQIKPDSSLQIIPTYSLPCSSRSQE
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (50%), Rat (50%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-62064. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
Glucagon is initially synthesized as proglucagon, which is 180 amino acids in length and is cleaved proteolytically. It contains a region corresponding to Glucagon itself, in addition to a signal peptide, spacer regions and two Glucagon-like peptide sequences. GLP1 is encoded by the fourth exon of the six in the human Glucagon gene. It is 37 amino acids in length and has 48% amino acid sequence homology to Glucagon, and is thought to have arisen by gene duplication. The sequence of GLP1 is conserved across many species, however, indicating that it has a particular function. GLP1 is a potent insulin secretagogue, renders pancreatic beta cells 'glucose-competent' and may be useful in the treatment of diabetes mellitus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GATA like protein 1; GATA like protein-1; GATA zinc finger domain containing 3; GATA-like protein 1; GATA-type zinc finger protein 1; GLP-1
Gene Aliases: GATAD3; GLP-1; GLP1; ZGLP1
UniProt ID: (Human) P0C6A0
Entrez Gene ID: (Human) 100125288
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