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Invitrogen
Human ZNF140 (aa 67-148) Control Fragment Recombinant Protein
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Product Details
RP-100882
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
GKREVKRDLFSVSESSGEIKDFSPKNVIYDDSSQYLIMERILSQGPVYSSFKGGWKCKDHTEMLQENQGCIRKVTVSHQEAL
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (28%), Rat (28%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-61714. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
The ZNF140 gene encodes a zinc finger protein that contains KRAB (Kruppel-associated box) domains, which are known to function as transcriptional repressors. These domains are located at the N-terminus of the protein and are involved in mediating protein-protein interactions, critical for gene silencing. ZNF140 is part of a large family of zinc finger proteins, which play significant roles in regulating gene expression by binding to specific DNA sequences. The KRAB domains of ZNF140 enable it to interact with other transcriptional repressors and recruit corepressor complexes, leading to chromatin remodeling and transcriptional repression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Zinc finger protein 140
Gene Aliases: pHZ-39; ZNF140
UniProt ID: (Human) P52738
Entrez Gene ID: (Human) 7699
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