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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (32%), Rat (32%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-60886. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The ZNF707 gene, a member of the zinc-finger protein (ZNF) family, encodes a transcription factor that can significantly influence various cellular processes by binding to DNA and regulating gene expression. Located on chromosome 4q32, zinc-finger proteins like ZNF707 are characterized by their zinc-finger motifs, which enable their interaction with specific DNA sequences. Mutations in ZNF707, such as rs4873815-TT, have been implicated in the tumorigenesis and prognosis of ovarian clear cell adenocarcinoma (Ov-CCA), highlighting its clinical significance in cancer research. Research also suggests that missense mutations in ZNF genes can alter protein-DNA interactions, potentially leading to cancer development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Zinc finger protein 707
Gene Aliases: ZNF707
UniProt ID: (Human) Q96C28
Entrez Gene ID: (Human) 286075
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