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Invitrogen
Mouse EphA4 Fc Chimera Recombinant Protein
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Product Details
RP-88233
Product Specifications
Species
Mouse
Expression System
HEK293 cells
Amino acid sequence
Mouse EPHA4, amino acids Met1-Thr547 (Accession # NP_031962.2) with a C-terminal human IgG1 Fc region
Tag
Fc-tag
Molecular weight
110 kDa
Class
Recombinant
Type
Protein
Purity
>95% as determined by SDS-PAGE.
Endotoxin concentration
<1.0 EU/µg
Activity
Measured by its binding ability in a functional ELISA. Immobilized mouse EPHA5 at 2 µg/ml (100 µL/well) can bind mouse EFNA4-Fc with a linear range of 1.28-32 ng/mL.
Conjugate
Form
Lyophilized
Purification
purified
Storage buffer
PBS, pH 7.4, with 0.01% mannitol, 5-8% trehalose, 0.01% Tween 80
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
It is recommended that the protein be aliquoted for optimal storage.
It is recommended that sterile water (1334 µL) be added to the vial to prepare a stock solution of 0.15 mg/mL.
Concentration is measured by UV.
Target Information
EPHA4 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EphA4 encodes a protein that binds ephrin-A ligands.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epa4; Ephrin type-A receptor 4; Tyrosine-protein kinase receptor MPK-3; Tyrosine-protein kinase receptor SEK-1
Gene Aliases: 2900005C20Rik; AI385584; Cek8; Epha4; Hek8; rb; Sek; Sek1; Tyro1
UniProt ID: (Mouse) Q03137
Entrez Gene ID: (Mouse) 13838
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