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Invitrogen
Mouse LILRB4 (CD85k, ILT3) Fc Chimera Recombinant Protein
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Product Details
RP-88246
Product Specifications
Species
Mouse
Expression System
HEK293 cells
Amino acid sequence
Mouse LILRB4, amino acids Met1-Lys238 (Accession # NP_038560.1) with a C-terminal human IgG1 Fc region
Tag
Fc-tag
Molecular weight
50.8 kDa
Class
Recombinant
Type
Protein
Purity
>95% as determined by SDS-PAGE.
Endotoxin concentration
<1.0 EU/µg
Conjugate
Form
Lyophilized
Purification
purified
Storage buffer
PBS, pH 7.4, with 0.01% mannitol, 5-8% trehalose, 0.01% Tween 80
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
It is recommended that the protein be aliquoted for optimal storage.
It is recommended that sterile water (599 µL) be added to the vial to prepare a stock solution of 1.67 mg/mL.
Concentration is measured by UV.
Target Information
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD85k; glycoprotein 49 B; leukocyte immunoglobulin-like receptor subfamily B member 4; Leukocyte immunoglobulin-like receptor subfamily B member 4A; Mast cell surface glycoprotein Gp49B
Gene Aliases: CD85K; gp49; Gp49b; HM18; ILT3; Lilrb4a; LIR-5
UniProt ID: (Mouse) Q64281
Entrez Gene ID: (Mouse) 14728
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