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Invitrogen
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This peptide corresponds to 15 amino acids near the carboxy terminus of mouse Raptor.
PEP-0242 can be used as a blocking peptide with polyclonal antibody PA5-20124.
Regulatory associated protein of mTOR (RAPTOR) is a binding partner of target of rapamycin (TOR). It binds to 4EBP1 and p70alpha. The binding of raptor to mTOR is essential for the mTOR-catalyzed phosphorylation of 4EBP1 in vitro. It enhances the mTOR kinase activity toward p70alpha. It is also an essential scaffold for the mTOR-catalyzed phosphorylation of 4EBP1 and mediates TOR action in vivo.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene Aliases: 4932417H02Rik; mKIAA1303; Rap; Raptor
Entrez Gene ID: (Mouse) 74370
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