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          • Proteins & Peptides ›
          • SARS-CoV-2 Spike Protein S1 Proteins

          Invitrogen

          SARS-CoV-2 Spike Protein S1 (B.1.1.7) His-Avi Tag Recombinant Protein, Biotin

          View all (87) SARS-CoV-2 Spike Protein S1 proteins

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          Cite SARS-CoV-2 Spike Protein S1 (B.1.1.7) His-Avi Tag Recombinant Protein, Biotin

          • Testing Data (1)
          SARS-CoV-2 Spike Protein S1 (B.1.1.7) His-Avi Tag Protein in SDS-PAGE (SDS-PAGE)
          Group 53 Created with Sketch.
          SARS-CoV-2 Spike Protein S1 (B.1.1.7) His-Avi Tag Protein in SDS-PAGE (SDS-PAGE)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          SARS-CoV-2 Spike Protein S1 (B.1.1.7) His-Avi Tag Protein (RP-88506) in SDS-PAGE

          SDS-PAGE analysis of SARS-CoV-2 Spike Protein S1 (B.1.1.7) His-Avi Tag (Product # RP-88506). The specification for purity shows: > 95 % (SDS-PAGE). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SARS-CoV-2 Spike Protein S1 (B.1.1.7) His-Avi Tag Protein in SDS-PAGE (SDS-PAGE)

          Product Details

          RP-88506

          Applications
          Tested Dilution
          Publications

          ELISA (ELISA)

          Assay-dependent
          -
          Product Specifications

          Species

          Virus

          Expression System

          HEK293 cells

          Amino acid sequence

          SARS-CoV-2 spike S1 (Accession # YP_009724390.1), amino acids Met1-Arg685 with (HV69-70, Y145) deletions and N501Y, A570D, D614G, P681H substitutions and a C-terminal His-tag and Avi-tag

          Tag

          His-tag, Avi-tag

          Molecular weight

          90.57 kDa

          Class

          Recombinant

          Type

          Protein

          Purity

          >95% as determined by SDS-PAGE.

          Endotoxin concentration

          <1.0 EU/µg

          Activity

          Immobilized ACE2 Protein, Human, Recombinant (mFc Tag) at 2 µg/mL (100 µL/well) can bind SARS-CoV-2 Spike S1 ( (HV69-70, Y145)deletion, N501Y, A570D, D614G, P681H) Protein (His and AVI Tag), Biotinylated, the EC50 of SARS-CoV-2 Spike S1 ( (HV69-70, Y145)deletion, N501Y, A570D, D614G, P681H) Protein (His and AVI Tag), Biotinylated is 30-150 ng/mL.

          Conjugate

          Biotin Biotin Biotin

          Form

          Lyophilized

          Purification

          purified

          Storage buffer

          PBS, pH 7.4, with 0.01% mannitol, 5-8% trehalose, 0.01% Tween 80

          Contains

          no preservative

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Wet ice

          Product Specific Information

          It is recommended that the protein be aliquoted for optimal storage.

          The mutations were identified in the SARS-CoV-2 varient known as B.1.1.7

          Target Information

          SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold symptoms to severe effects including death and respiratory distress. SARS-CoV-2 Spike Protein is composed of S1 domain and S2 domain (Spike Protein). The Spike protein is the main surface antigen of the coronavirus. The glycosylated Spike protein (as well as the nucleocapsid protein) can be detected in infected cell culture supernatants with antisera from SARS patients. S1 contains a receptor-binding domain (RBD) that can specifically bind to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells. CoV diversity is reflected in the variable Spike proteins (S proteins), which have evolved into forms differing in their receptor interactions and their response to various environmental triggers of virus-cell membrane fusion.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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