C1QBP Proteins

Protein Information

Replication Protein A (RPA) (also known as human single-stranded DNA binding protein, or HSSB) is involved in DNA replication, repair, and recombination. RPA from human cells is a stable heterotrimer of 70kDa, 32-34kDa, and 11-14kDa subunits (RPA70, RPA32, and RPA14 respectively). RPA is required for the SV40 large tumor antigen-catalyzed unwinding of SV40 DNA and stimulates DNA polymerase alpha and delta. RPA34 is phosphorylated at the G1/S boundary of the cell cycle or upon exposure of cells to DNA damage-inducing agents including ionizing and UV radiation.

Synonyms

AA407365; AA986492; ASF/SF2-associated protein p32; C1q globular domain-binding protein; C1qbp; complement C1q binding protein; complement component 1 Q subcomponent-binding protein, mitochondrial; complement component 1, q subcomponent binding protein; D11Wsu182e; GC1QBP; gC1qR; gC1Q-R; gC1q-R protein; Glycoprotein gC1qBP; Habp1; Hyaluronan-binding protein 1; mitochondrial matrix protein p32; p32; p33; RPA; SF2AP32; SF2P32; splicing factor SF2-associated protein