GSTA1 Proteins

Protein Information

This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. This action is an important step in detoxification of these compounds. This subfamily of enzymes has a particular role in protecting cells from reactive oxygen species and the products of peroxidation. Polymorphisms in this gene influence the ability of individuals to metabolize different drugs. This gene is located in a cluster of similar genes and pseudogenes on chromosome 6. Alternative splicing results in multiple transcript variants.

Synonyms

13-hydroperoxyoctadecadienoate peroxidase; Androst-5-ene-3,17-dione isomerase; class alpha; glutathione S-alkyltransferase A1; glutathione S-aryltransferase A1; glutathione S-transferase; glutathione S-transferase 2; glutathione S-transferase A1; Glutathione S-transferase A1, N-terminally processed; glutathione S-transferase A3 subunit; glutathione S-transferase A5; glutathione S-transferase alpha 1; glutathione S-transferase alpha M14; Glutathione S-transferase alpha M14, N-terminally processed; Glutathione S-transferase alpha-3; glutathione S-transferase Ha subunit 1; Glutathione S-transferase Ya; Glutathione S-transferase Ya1; glutathione S-transferase Yc-1; glutathione S-transferase Yc1 subunit; glutathione S-transferase, alpha 1 (Ya); Glutathione-S-transferase alpha type (Ya); GST; GST 2-2; GST A3-3; GST AA; GST class-alpha; GST class-alpha member 1; GST HA subunit 1; GST Yc1; GST2; Gst2-1; Gsta; GSTA1; GSTA1-1; Gsta3; Gsta5; GST-epsilon; Gstya; Gstyc1; GTH1; OTTMUSG00000031890; RP11-392A23.1; S-(hydroxyalkyl)glutathione lyase A1; testicular tissue protein Li 80; Yc1