ITGA7 (Integrin alpha 7) Proteins

Protein Information

Integrin alpha-7 is a protein that in humans is encoded by the ITGA7 gene. This gene is mapped to 12q13.2. The protein encoded by this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis. This protein functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in this gene are associated with congenital myopathy.

Synonyms

[a]7; alpha 7A integrin; alpha7; H36-alpha7; integrin alpha 7; integrin alpha 7 chain; integrin alpha-7; Integrin alpha-7 70 kDa form; Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; integrin subunit alpha 7; integrin, alpha 7; Itga7; UNQ406/PRO768