LRRK2 Proteins

Protein Information

LRRK2 (Leucine Rich Repeat Kinase 2) is a Protein Coding gene. Diseases associated with LRRK2 include Parkinson Disease 8, Autosomal Dominant and Hereditary Late-Onset Parkinson Disease. Among its related pathways are Signaling by PTK6 and ncRNAs involved in Wnt signaling in hepatocellular carcinoma. Gene Ontology (GO) annotations related to LRRK2 (G2019S Mutant) include protein homodimerization activity and transferase activity, transferring phosphorus-containing groups. An important paralog of LRRK2 (G2019S Mutant) is TNNI3K. Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene, which codes for a multidomain protein kinase, are considered the most common genetic cause of late-onset autosomal-dominant Parkinson's disease.

Synonyms

LRRK2