MUC13 Proteins

Protein Information

Mucin 13, epithelial transmembrane. SEA is an extracellular domain associated with O-glycosylation. Proteins found to contain SEA-modules include, agrin, enterokinase, 63 kDa sea urchin (Strongylocentrotus purpuratus) sperm protein, perlecan (heparan sulphate proteoglycan core, mucin 1 and the cell surface antigen, 114/A10, and two functionally uncharacterised, probably extracellular, Caenorhabditis elegans proteins. Despite the functional diversity of these adhesive proteins, a common denominator seems to be their existence in heavily glycosylated environments. In addition, the better characterised proteins all contain O-glycosidic-linked carbohydrates such as heparan sulphate that contribute considerably to their molecular masses. The common module might regulate or assist binding to neighbouring carbohydrate moieties. Enterokinase, the initiator of intestinal digestion, is a mosaic protease composed of a distinctive assortment of domains.

Synonyms

114/A10; 14/A10; AI159736; Cell surface antigen 114/A10; Down-regulated in colon cancer 1; DRCC1; Lrrp; Ly64; Lymphocyte antigen 64; Muc-123; MUC13; MUC-13; mucin 13; mucin 13, cell surface associated; mucin 13, epithelial transmembrane; Mucin-13; NJ-1; RECC; UNQ6194/PRO20221