RFX2 Proteins

Protein Information

This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq, Jul 2008].

Synonyms

DNA binding protein RFX2; DNA-binding protein RFX2; FLJ14226; HLA class II regulatory factor RFX2; regulatory factor X 2; regulatory factor X, 2 (influences HLA class II expression); regulatory factor X2; RFX2; trans-acting regulatory factor 2