SH3RF1 Proteins

Protein Information

This gene encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network. The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, facilitating the formation of a functional signaling module.

Synonyms

2200003J05Rik; E3 ubiquitin-protein ligase SH3RF1; FLJ21602; KIAA1494; plenty of SH3 domains; plenty of SH3s; Posh; Posh1; Protein POSH; putative E3 ubiquitin-protein ligase SH3RF1; putative scaffolding protein POSH; R75531; RING finger protein 142; RING-type E3 ubiquitin transferase SH3RF1; RNF142; SH3 domain containing ring finger 1; SH3 domain-containing RING finger protein 1; SH3 multiple domains 2; SH3 multiple domains protein 2; Sh3md2; Sh3rf1