TAP Proteins

Protein Information

The constitutive transport element (CTE) of type D retroviruses serves as a signal of nuclear export for unspliced viral RNAs. TAP (also known as NXF1) mediates the export of CTE-containing simian type D retroviral RNAs through binding directly to the CTE. TAP is associated with a recognized mRNA export pathway and is a member of the multigene family of NXF proteins. NXF proteins belong to an evolutionarily conserved family of proteins, which are characterized by a leucine-rich-repeat domain (LRR) followed by a region known as the Nuclear Transport Factor 2 (NTF2)-like domain.

Synonyms

Mex 67 homolog; MEX67; Mex67h; modifier of vibrator 1; mRNA export factor TAP; Mvb1; Nuclear RNA export factor 1; nuclear RNA export factor 1 homolog; NXF1; Tap; tip associated protein; tip associating protein; tip-associated protein; Tip-associating protein; Vdp