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          • Proteins & Peptides ›
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          TIRAP Proteins

          TIRAP peptides and recombinant proteins are available for Human and Mouse. These Protein have been validated for use in the following applications: Blocking Assay. Available Product Grades: RUO. Browse all 3 proteins. Not finding the exact protein, grade or size needed?... TIRAP peptides and recombinant proteins are available for Human and Mouse. These Protein have been validated for use in the following applications: Blocking Assay. Available Product Grades: RUO. Browse all 3 proteins. Not finding the exact protein, grade or size needed? Contact us... TIRAP peptides and recombinant proteins are available for Human and Mouse. These Protein have been validated for use in the following applications: Blocking Assay. Available Product Grades: RUO. Browse all 3 proteins. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.... TIRAP peptides and recombinant proteins are available for Human and Mouse. These Protein have been validated for use in the following applications: Blocking Assay. Available Product Grades: RUO. Browse all 3 proteins. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.

          Protein Information

          Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as TIRAP and MyD88 to activate various kinases and transcription factors. In TIRAP-deficient mice, TLR signaling in response to TLR2 ligands (using either TLR1 and TLR6 as co-receptors) is totally abolished, suggesting that MyD88 and TIRAP work together and are both required for TLR2 signaling. Furthermore, these mice are also resistant to the toxic effects of LPS and show defects in NF-βB and MAP kinase activation, suggesting that TIRAP is also involed in TLR4 signaling.

          Synonyms

          AA407980; adapter protein wyatt; adaptor protein Wyatt; BACTS1; C130027E04Rik; FLJ42305; HGNC:17192; Mal; MyD88 adapter-like protein; MyD88-2; OTTHUMP00000179130; TIR domain containing adaptor protein; TIR domain-containing adapter protein; TIRAP; Tlr4ap; toll/interleukin-1 receptor domain-containing adapter protein; toll-interleukin 1 receptor (TIR) domain containing adaptor protein; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein; Toll-like receptor 4 adaptor protein; Toll-like receptor adaptor protein; Wyatt

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Invitrogen
          Human TIRAP (aa 79-162) Control Fragment Recombinant Protein
          Invitrogen
          Human TIRAP (aa 79-162) Control Fragment Recombinant Protein
          Host
          Species
          Human
          Expression System
          E. coli
          Product Grade
          Research Use Only
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          Ctrl BLOCK
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          Special offer
          Online exclusive
          Online offer:
          Cat # RP-97392

          100 µL

          Invitrogen
          Human TIRAP Synthetic Peptide
          Invitrogen
          Human TIRAP Synthetic Peptide
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          Species
          Human
          Expression System
          Product Grade
          Research Use Only
          Application
          Ctrl BLOCK
          Price
          Special offer
          Online exclusive
          Online offer:
          Cat # PEP-0146

          50 µg

          Invitrogen
          Mouse TIRAP Synthetic Peptide
          Invitrogen
          Mouse TIRAP Synthetic Peptide
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          Species
          Mouse
          Expression System
          Product Grade
          Research Use Only
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          Ctrl BLOCK
          Price
          Special offer
          Online exclusive
          Online offer:
          Cat # PEP-0147

          50 µg

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