Virtual Event
May 26, 2021 - May 26, 2021
Reveal 2021

Cryo-electron microscopy, mass spectrometry and structural biology online event.

Watch on-demand

This event took place on May 26, 2021. Watch the on-demand recordings to learn how combining mass spectrometry and cryo-EM allows structural biologists to achieve unparalleled results in their quest to understand macromolecular functions. You will also hear from researchers whose cryo-EM work drove the development of the covid-19 vaccine and what the future holds for vaccine development.

Reveal 2021 on-demand sessions

Electrospray ion beam disposition: Preparative mass spectrometry for single molecule imaging
Speaker: Stephan Rauschenbach, Professor and Tutorial Fellow in Physical Chemistry, University of Oxford

Stephan Rauschenbach, Professor and Tutorial Fellow in Physical Chemistry, University of Oxford

Professor Stephan Rauschenbach’s research focuses on preparative mass spectrometry, a method of handling even the largest of molecules to make them accessible at the individual molecule level that is useful for atomically resolved single-molecule imaging as well as for the fabrication of functional molecular coatings mimicking biological concepts.

He began work on his PhD at the Max Planck Institute for Solid State Research in Stuttgart and completed his dissertation at the École Polytechnique Fédérale de Lausanne, after which he became group leader at the Max Planck Institute and began teaching in the physics department at the University of Konstanz.
Crosslinking mass spectrometry for cryo-EM
Speaker: Juri Rappsilber, Professor of Bioanalytics, Technische Universität Berlin

Juri Rappsilber, Professor of Bioanalytics, Technische Universität Berlin

Dr. Rappsilber studied chemistry at the Technische Universität Berlin, Strathclyde University, and Harvard Medical School. He earned his PhD jointly from the European Molecular Biology Laboratory Heidelberg and the Johann Wolfgang Goethe University in Frankfurt, Germany, where he worked in the laboratory of Matthias Mann on the mass spectrometric analysis of protein complexes. He completed a postdoctoral fellowship at the University of Southern Denmark, Odense, and in 2006 he joined the Wellcome Centre for Cell Biology, University of Edinburgh, twice obtaining Wellcome Trust Senior Research Fellowships. Dr. Juri Rappsilber is currently a professor of bioanalytics at the Technische Universität in Berlin. He combines organic chemistry and computational sciences with advanced mass spectrometry to expand the frontiers of our understanding of the structural and mechanistic basis of how cells work.
Peering inside SARS-COV-2 using high-resolution imaging
Speaker: Dr. Deborah Kelly, Professor of Biomedical Engineering, Pennsylvania State University

Dr. Deborah Kelly, Professor of Biomedical Engineering, Pennsylvania State University

Dr. Kelly developed technical breakthroughs in the field of cryo-electron microscopy (cryo-EM) that are now also being used by the liquid-phase EM community. As interest in high-resolution imaging has skyrocketed in recent years, the Kelly team has been on the leading edge of adapting these tools for biomedical applications involving human viruses and cancer.

She completed her PhD in molecular biophysics at Florida State University and her post-doctoral training in structural biology at Harvard Medical School. She currently holds the Lloyd and Dottie Foehr Huck Chair in molecular biophysics and directs the Center for Structural Oncology (CSO) at Penn State. The CSO aims to combats molecular culprits of human disease by revealing their hidden vulnerabilities.
Live panel discussion


Join our live panel discussion with experts from Thermo Fisher Scientific and current customers to hear their thoughts on the future of cryo-EM in life sciences research and how it will accelerate our knowledge and understanding of even more intricate systems, like pathways and organelles, on the journey from structure to function.

The power of structure in disease research
Speaker: Dr. Erica Ollmann Saphire, Professor, La Jolla Institute for Immunology

Dr. Erica Ollmann Saphire, Professor, La Jolla Institute for Immunology

Dr. Saphire is the recipient of numerous accolades and grants including a Presidential Early Career Award for Scientists and Engineers; the Global Virus Network Robert C. Gallo Award for Scientific Excellence and Leadership; and young investigator awards from the International Society of Antiviral Research, the American Society for Microbiology, the American Society for Biochemistry and Molecular Biology, and the MRC Centre for Virus Research in the United Kingdom.

She has also received a Fulbright Global Scholar Award as well as a Mercator Fellowship from the German Research Foundation. Dr. Saphire received a BA in biochemistry and cell biology and ecology and evolutionary biology from Rice University in Houston, Texas, and a PhD in molecular biology from Scripps Research.

Register to watch the on-demand Reveal 2021 sessions