One nucleic acid extraction kit can be used for multiple microbiological organisms and multiple infectious disease research applications. Applied Biosystem™ MagMAX Prime Viral/Pathogen NA Isolation Kit utilizes magnetic bead-based technology to purify and isolate viral, bacterial, fungal and parasitic nucleic acid from a variety of human biological specimens for downstream applications like qPCR and NGS. 

Pathogens are disease causing bacteria, virus and fungi which can infect animals and plants. Bacteria are microscopic pathogens that reproduce quickly upon entering the body. They tend to release toxins that can damage tissues and cause illness. Whereas viruses smaller than bacteria invade a host cell then replicate, producing hundreds and thousands of new viruses to infect other host cells. Fungi are spore producing organisms that can sometimes cause diseases. 

Researching pathogens using one solution for a multitude sample types

To start researching pathogenic organisms, research labs can use a combination of kits and reagents along with automation instruments that support with isolation of nucleic acid from your chosen sample type. The DNA and RNA can then be analyzed using several different instruments and techniques, such as dPCR and NGS. Learn more about nucleic acid purification for infectious disease research. 

Simplify your sample preparation by using one kit to cover a multitude of sample types. MagMAX Prime Viral/Pathogen NA Isolation Kit can help improve your infectious research through:

• Advanced formulation—Maximize nucleic acid yield for greater assay sensitivity
  • Improve yield and achieve earlier amplification by up to 2.5 C_t when isolating some pathogenic targets.*
  • Less viscosity making it easier to pipette  
  • Versatility in workflow options
  • Optimized formulation 
• Streamlined and simple workflow
  • Enable multiple applications like STI, GI, UTI, RTI, and lesion with one single solution reducing the need for multiple kits
  • Three simple workflows
  • One user guide
• Sample type versatility—enable high-quality nucleic acid isolation from a variety of biological samples such as swabs in transport media (respiratory, genital, and lesion swabs), saliva, stool, urine, plasma, and serum
• Compatible with automation—pair it with KingFisher Purification Instrument for rapid extraction and enable 96 samples to be processed in less than 60 minutes
• Sustainable design—This kit consists of biodegradable reagents that are REACH** compliant
  • Paperless documentation—User available digitally* and easily accessible with a QR code printed on the box
  • Less hazardous—All reagents are REACH compliant
  • Greener surfactants—Biodegradable detergent
  • Responsibly packaged—Compact product packaging size
• Flexible configuration available—Flexible user filled and prefilled kitted*** configuration for easy ordering. Additional accessories available for advanced lysis and stool workflows. Also available in large stand-alone component format. 

*Cycle Threshold (C_t) evaluation dependent on assay and workflow. We encourage all workflows and assay evaluations to be conducted by the customer.
**REACH is a regulation of the European Union, adopted to improve the protection of human health and the environment from the risks that can be posed by chemicals. Understanding REACH—ECHA (europa.eu)
***Prefilled kit only available for purchase in North America. Please contact your local representative to learn more.

A complete and simplified infectious disease workflow with MagMAX Prime Viral/Pathogen NA Isolation Kit with KingFisher Purification System. 

Less than 0.5% risk to contamination evaluated across multiple instruments, workflows and users stemming from reagent movement on a KingFisher instrument

Basic workflow confirmed the amplification of nucleic acid across bloodborne, Respiratory Tract Infection (RTI), Sexually Transmitted Infection (STI)/Urinary Tract Infection (UTI) applications at varying concentrations

Advanced lysis and advanced stool workflows confirmed the amplification of nucleic acid across Sexually Transmitted Infection (STI)/Urinary Tract Infection (UTI) and Gastrointestinal Infection (GI) applications respectively at varying concentrations

Prefilled kits saved the user an average of 10 mins compared to user-filled kits

Extract nucleic acids using an automated platform in ≤45 minutes with a prefilled workflow*

Know which additional accessory to select when working with difficult pathogen types.  

See below for a list of available reagents and wash solutions for the MagMAX Prime Viral/Pathogen NA Isolation Kit

• Applied Biosystems MagMAX Prime Viral/Pathogen NA Isolation Kit
• Applied Biosystems MagMAX Prime Viral/Pathogen NA Isolation Kit, Prefilled Plate
• Applied Biosystems MagMAX Prime Viral/Pathogen Binding Beads
• Applied Biosystems MagMAX Prime Viral/Pathogen Elution Buffer
• Applied Biosystems MagMAX Prime Viral/Pathogen Wash I Solution
• Applied Biosystems MagMAX Prime Viral/Pathogen Binding Solution
• Applied Biosystems MagMAX Prime Viral/Pathogen Proteinase K
• Applied Biosystems MagMAX Prime Viral/Pathogen Proteinase K dye
• Applied Biosystems MagMAX Prime G+ Bacteria and Fungal Lysis Buffer, 1000
• Applied Biosystems MagMAX Prime Stool Lysis Buffer
• Applied Biosystems MagMAX Prime Bead Beating Tubes
• Applied Biosystems MagMAX Prime G+ Bacteria and Fungal Lysis Buffer, 100