Hamburger Menu Button
Thermo Fisher Scientific Logo
Sign in
Don't have an account ? Create Account
  • Products
    • Antibodies
    • Cell Culture Media
    • Chemicals
    • Chromatography Columns and Cartridges
    • Lab Equipment
    • Lab Plasticware and Supplies
    • Microplates
    • Oligos, Primers, Probes and Genes
    • TaqMan Real-Time PCR Assays
    • Greener Products
    • See all product categories
  • Applications
    • Bioprocessing
    • Cell Culture and Transfection
    • Cell and Gene Therapy
    • Chromatography
    • Molecular Testing
    • Digital Solutions
    • DNA and RNA Extraction and Analysis
    • Spectroscopy, Elemental and Isotope Analysis
    • See all applications and techniques
  • Services
    • 360° CDMO and CRO Solutions
    • CDMO Services
    • CRO Services
    • Custom Services
    • Enterprise Services
    • Financial and Leasing Services
    • Instrument Services
    • Lab Informatics
    • OEM and Commercial Supply
    • Training Services
    • Unity Lab Services
    • See all services
  • Help and Support
    • How to Order
    • Instrument Support
    • Learning Centers
    • Register for an Account
    • Technical Support Centers
    • See all help and support topics
  • Popular
    • TaqMan Real-Time PCR Assays
      TaqMan Real-Time PCR Assays
    • Antibodies
      Antibodies
    • Oligos, Primers & Probes
      Oligos, Primers & Probes
    • GeneArt Gene Synthesis
      GeneArt Gene Synthesis
    • Cell Culture Plastics
      Cell Culture Plastics
  • Contact Us
  • Quick Order
  • Order Status and Tracking
  • Documents and Certificates
Thermo Fisher Scientific Logo

Search Thermo Fisher Scientific

Search All
Search button Close
          • Order Status
          • Quick Order
          • Sign in
            Sign in
            Don't have an account ? Create Account
            • Account
            • Check Order Status
            • Aspire Member Program
            • Connect: Lab, Data, Apps
            • Custom Products & Projects
            • Services Central
          This product has been added to your favorites list. Go to My Favorites

          System Message

          OKCancel
          LOADING ...
          • Home
          • › Search Tool
          • › Search Results
          • › Hs00233287_m1
          See other IKBKB GE Assays ›
          Gene Symbol:
          IKBKB
          Gene Name:
          inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
          Gene Aliases:
          IKK-beta, IKK2, IKKB, IMD15, NFKBIKB
          Chromosome Location:
          Chr.8: 42271302 - 42332653 on Build GRCh38
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          Assay ID Hs00233287_m1
          Size
          Availability Inventoried
          Catalog # 4331182
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • Assay Details
          • More Information
          • Citations (1)

          Genomic Map

          LOADING...
          ×
          Back To Top

          Assay Details

          Gene Symbol: IKBKB
          Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
          RefSeq NM_001190720.2 NP_001177649.1 7 - 8 758 61
          NM_001242778.1 NP_001229707.1 7 - 8 786 61
          NM_001556.2 NP_001547.1 8 - 9 881 61
          NR_033818.1 8 - 9 937 61
          NR_033819.1 8 - 9 881 61
          NR_040009.1 8 - 9 881 61
          XM_005273490.2 XP_005273547.1 8 - 9 881 61
          XM_005273491.4 XP_005273548.1 7 - 8 781 61
          XM_005273492.3 XP_005273549.1 8 - 9 881 61
          XM_005273493.3 XP_005273550.1 5 - 6 577 61
          XM_005273494.2 XP_005273551.1 8 - 9 881 61
          XM_011544517.2 XP_011542819.1 8 - 9 879 61
          XM_011544519.2 XP_011542821.1 7 - 8 749 61
          XM_011544520.2 XP_011542822.1 5 - 6 596 61
          XM_011544522.2 XP_011542824.1 5 - 6 557 61
          XM_017013396.1 XP_016868885.1 7 - 8 834 61
          GenBank mRNA AB209090.1 - 7 - 8 699 61
          AF029684.1 - 7 - 8 695 61
          AF031416.1 - 7 - 8 695 61
          AF080158.1 - 8 - 9 838 61
          AK290952.1 - 8 - 9 747 61
          AK298241.1 - 5 - 6 445 61
          AK302723.1 - 7 - 8 742 61
          AK303294.1 - 7 - 8 770 61
          AK303528.1 - 7 - 8 774 61
          AK316418.1 - 7 - 8 742 61
          BC108694.1 - 8 - 9 793 5784717 61
          BC144080.1 - 7 - 8 725 61
          BX648165.1 - 7 - 8 1333 61

          Back To Top

          More Information


          Updated Mapping Information

          This assay targets the same location as Clariom D transcript cluster(s) TC0800007435.hg.1
          This assay targets the same location as HTA transcript cluster(s) TC08000325.hg.1

          Additional Information:

          This assay is in the 5'UTR region of the XM_011544522.2,XM_017013396.1 transcripts.

          Set Membership:

          Ambion siRNA available Amplicon length less than or equal to 70 Protein Kinase Mammalian Gene Collection Homo sapiens Human PDGF Pathway Human iNOS Signaling Human CMV and MAPK Pathways Human IL-2 Pathway Human TNFR2 Pathway Human Signal Transduction Pathways Human NGF Pathway Human EGF Pathway Human IL-1 Pathway Human Toll-Like Receptors Pathway Human TNFR1 Pathway Human Apoptotic Pathways triggered by HIV1 Human TNF Superfamily Pathway Human Toll Pathway Core Components HUMAN FAS SIGNALING HUMAN PI3K SIGNALING IN B-LYMPHOCYTE HUMAN APOPTOSIS THROUGH DEATH RECEPTORS HUMAN GPCR PATHWAY HUMAN THROMBIN SIGNALING HUMAN IGF1R SIGNALING HUMAN IL-3 PATHWAY HUMAN IL-6 PATHWAY HUMAN CELLULAR APOPTOSIS PATHWAY Inventoried Human_TNFR2_Pathway Human_Toll_Pathway_Core_Components Human_EGF_Pathway Human_PDGF_Pathway Human_Toll-Like_Receptors_Pathway Human_IL-1_Pathway Human_iNOS_Signaling Human_TNFR1_Pathway Human_Signal_Transduction_Pathways Human_NGF_Pathway Human_IL-2_Pathway Human_TNF_Superfamily_Pathway Human_Apoptotic_Pathways_Triggered_by_HIV1 Human_IL-6_Pathway Human_IL-3_Pathway Human_PI3K_Signaling_in_B-Lymphocyte Human_Apoptosis_through_Death_Receptors Human_GPCR_Pathway Human_Thrombin_Signaling Human_Fas_Signaling Human_Cellular_Apoptosis_Pathway Human_IGF1R_Signaling Probe spans exons

          Matching Ambion siRNAs:

          Click here to find siRNAs for Gene IKBKB

          Panther Classification:

          Molecular Function -

          non-receptor serine/threonine protein kinase protein modifying enzyme

          Gene Ontology Categories:

          Function(s) Process(es)

          stimulatory C-type lectin receptor signaling pathway
          skeletal muscle contraction
          protein phosphorylation
          inflammatory response
          I-kappaB kinase/NF-kappaB signaling
          I-kappaB phosphorylation
          positive regulation of cell proliferation
          response to virus
          response to toxic substance
          regulation of tumor necrosis factor-mediated signaling pathway
          positive regulation of neuron projection development
          cortical actin cytoskeleton organization
          neuron projection development
          response to lipopolysaccharide
          tumor necrosis factor-mediated signaling pathway
          negative regulation of myosin-light-chain-phosphatase activity
          TRIF-dependent toll-like receptor signaling pathway
          Fc-epsilon receptor signaling pathway
          regulation of phosphorylation
          response to drug
          serine phosphorylation of STAT protein
          negative regulation of apoptotic process
          positive regulation of I-kappaB kinase/NF-kappaB signaling
          innate immune response
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          T cell receptor signaling pathway
          positive regulation of NF-kappaB transcription factor activity
          stress-activated MAPK cascade
          nucleotide-binding oligomerization domain containing signaling pathway
          interleukin-1-mediated signaling pathway
          response to fatty acid
          cellular response to tumor necrosis factor
          establishment of protein localization to plasma membrane
          positive regulation of neuron death
          regulation of establishment of endothelial barrier
          negative regulation of bicellular tight junction assembly
          protein kinase activity
          protein serine/threonine kinase activity
          protein binding
          ATP binding
          IkappaB kinase activity
          protein kinase binding
          protein homodimerization activity
          protein heterodimerization activity
          scaffold protein binding

          MicroArray Probes:

          Affymetrix

          Array Name Probe IDs Targets Target Type
          Affymetrix Human Transcriptome Array 2.0 PSR08004639.hg.1 TC08000325.hg.1 HTA TC
          Affymetrix Human Transcriptome Array 2.0 PSR08004639.hg.1 ENST00000379708.3 Ensembl
          Affymetrix Human Transcriptome Array 2.0 PSR08004639.hg.1 ENST00000416505.2 Ensembl
          Affymetrix Human Transcriptome Array 2.0 PSR08004639.hg.1 ENST00000520810.1 Ensembl
          Affymetrix Human Transcriptome Array 2.0 PSR08004639.hg.1 ENST00000520835.1 Ensembl
          Affymetrix Human Transcriptome Array 2.0 PSR08004639.hg.1 NM_001190720.2 Refseq
          Affymetrix Human Transcriptome Array 2.0 PSR08004639.hg.1 NM_001242778.1 Refseq
          Affymetrix Human Transcriptome Array 2.0 PSR08004639.hg.1 NM_001556.2 Refseq
          Affymetrix Human Transcriptome Array 2.0 PSR08004639.hg.1 NR_033818.1 Refseq
          Affymetrix Human Transcriptome Array 2.0 PSR08004639.hg.1 NR_033819.1 Refseq
          Affymetrix Human Transcriptome Array 2.0 PSR08004639.hg.1 NR_040009.1 Refseq
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 ENST00000342222.6 Ensembl
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 ENST00000416505.5 Ensembl
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 ENST00000517890.5 Ensembl
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 ENST00000517917.5 Ensembl
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 ENST00000518647.5 Ensembl
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 ENST00000518679.5 Ensembl
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 ENST00000520201.5 Ensembl
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 ENST00000520655.5 Ensembl
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 ENST00000520810.5 Ensembl
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 ENST00000520835.5 Ensembl
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 ENST00000521661.5 Ensembl
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 ENST00000522545.1 Ensembl
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 ENST00000523105.5 Ensembl
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 ENST00000523517.5 Ensembl
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 ENST00000629753.1 Ensembl
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 NM_001190720.2 Refseq
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 NM_001242778.1 Refseq
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 NM_001556.2 Refseq
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 NR_033818.1 Refseq
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 NR_033819.1 Refseq
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 NR_040009.1 Refseq
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 ENST00000342222.6 Ensembl
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 ENST00000416505.5 Ensembl
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 ENST00000517890.5 Ensembl
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 ENST00000517917.5 Ensembl
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 ENST00000518647.5 Ensembl
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 ENST00000518679.5 Ensembl
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 ENST00000520201.5 Ensembl
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 ENST00000520655.5 Ensembl
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 ENST00000520810.5 Ensembl
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 ENST00000520835.5 Ensembl
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 ENST00000521661.5 Ensembl
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 ENST00000522545.1 Ensembl
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 ENST00000523105.5 Ensembl
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 ENST00000523517.5 Ensembl
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 ENST00000629753.1 Ensembl
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 NM_001190720.2 Refseq
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 NM_001242778.1 Refseq
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 NM_001556.2 Refseq
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 NR_033818.1 Refseq
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 NR_033819.1 Refseq
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 NR_040009.1 Refseq
          Affymetrix Human Clariom D Assay PSR0800151373.hg.1 TC0800007435.hg.1 Clariom D TC

          Back To Top
           

          Citations (1)

          NAK is recruited to the TNFR1 complex in a TNFalpha-dependent manner and mediates the production of RANTES: identification of endogenous TNFR-interacting proteins by a proteomic approach.
          Authors
          Kuai J, Wooters J, Hall JP, Rao VR, Nickbarg E, Li B, Chatterjee-Kishore M, Qiu Y, Lin LL
          Journal
          J Biol Chem - Page No 53266 (Fri Dec 17 00:00:00 EST 2004)
          Volume (Year)
          279 (2004)
          Product Usage
          -

          Back To Top

          Related Products

          • TaqMan® Fast Advanced Master Mix
          • SuperScript® VILO™ cDNA Synthesis Kit
          Ordering Plus Icon Minus Icon
          • Order Status
          • Order Help
          • Quick Order
          • Supply Center
          • eProcurement
          Support Plus Icon Minus Icon
          • Help and Support
          • Contact Us
          • Technical Support Centers
          • Documents and Certificates
          • Report a Site Issue
          Resources Plus Icon Minus Icon
          • Learning Centers
          • Promotions
          • Events and Webinars
          • Social Media
          About Thermo Fisher Plus Icon Minus Icon
          • About Us
          • Careers
          • Investors
          • News
          • Social Responsibility
          • Trademarks
          • Consumer Health Data Privacy Policy
          Our Portfolio Plus Icon Minus Icon
          • Thermo Scientific
          • Applied Biosystems
          • Invitrogen
          • Gibco
          • Ion Torrent
          • Fisher Scientific
          • Unity Lab Services
          • Patheon
          • PPD
          • Terms & Conditions
          • Privacy Information Center
          • Price & Freight Policy
          © 2006-2025 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified.
          United States flag icon
          United States

          Your items have has been added!


          Host server : magellan-search-74594944d-pk6zc:80/100.66.130.62:80.
          git-commit: ab2b2261c2971e97b1ae408e3ad10520b8413932
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.31.0-2025.06.23-1.0