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          • Home
          • › Search Tool
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          • › Mm00446190_m1
          See other IL6 GE Assays ›
          Gene Symbol:
          Il6
          Gene Name:
          interleukin 6
          Gene Aliases:
          Il-6
          Chromosome Location:
          Chr.5: 30013161 - 30019968 on Build GRCm38
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          Assay ID Mm00446190_m1
          Best Coverage
          Size
          Availability Inventoried
          Catalog # 4331182
          Price
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          • Genomic Map
          • Assay Details
          • More Information
          • Citations (74)

          Genomic Map

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          Assay Details

          Gene Symbol: Il6
          Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
          RefSeq NM_031168.1 NP_112445.1 2 - 3 237 78
          GenBank mRNA AK089780.1 - 2 - 3 256 78
          AK150440.1 - 2 - 3 256 78
          AK152189.1 - 1 - 2 243 78
          BC132458.1 - 2 - 3 230 40130735 78
          BC138766.1 - 2 - 3 230 8861788 78
          BC145409.1 - 2 - 3 230 78
          DQ788722.1 - 2 - 3 206 78
          J03783.1 - 2 - 3 254 78
          X06203.1 - 2 - 3 239 78
          X54542.1 - 2 - 3 237 78

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          More Information


          Set Membership:

          Ambion siRNA available Amplicon length between 71 and 85 Apoptosis Mammalian Gene Collection Recommended Assay Mus musculus Mouse Androgen Panel Mouse Chemokine Panel Mouse Immune Response Mouse Alzheimer's Disease Inventoried Mouse_Immune_Response Mouse_Alzheimer Probe spans exons

          Matching Ambion siRNAs:

          Click here to find siRNAs for Gene Il6

          Gene Ontology Categories:

          Function(s) Process(es)

          neutrophil apoptotic process
          myeloid cell homeostasis
          hepatic immune response
          positive regulation of acute inflammatory response
          negative regulation of protein kinase activity
          acute-phase response
          inflammatory response
          immune response
          positive regulation of cell proliferation
          negative regulation of cell proliferation
          regulation of cell shape
          response to wounding
          regulation of vascular endothelial growth factor production
          positive regulation of gene expression
          cell growth
          cytokine-mediated signaling pathway
          endocrine pancreas development
          neuron projection development
          positive regulation of chemokine production
          positive regulation of interleukin-6 production
          negative regulation of collagen biosynthetic process
          positive regulation of peptidyl-serine phosphorylation
          positive regulation of protein import into nucleus, translocation
          positive regulation of T cell proliferation
          T cell activation
          regulation of cell proliferation
          positive regulation of tyrosine phosphorylation of Stat3 protein
          glucose homeostasis
          defense response to protozoan
          regulation of apoptotic process
          positive regulation of apoptotic process
          negative regulation of apoptotic process
          negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
          positive regulation of MAPK cascade
          negative regulation of chemokine biosynthetic process
          regulation of circadian sleep/wake cycle, non-REM sleep
          positive regulation of nitric oxide biosynthetic process
          cell redox homeostasis
          positive regulation of T-helper 2 cell differentiation
          positive regulation of neuron differentiation
          negative regulation of gluconeogenesis
          positive regulation of translation
          positive regulation of DNA replication
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          positive regulation of JAK-STAT cascade
          muscle cell cellular homeostasis
          negative regulation of hormone secretion
          negative regulation of muscle organ development
          positive regulation of smooth muscle cell proliferation
          positive regulation of epithelial cell proliferation
          negative regulation of cytokine secretion
          positive regulation of peptidyl-tyrosine phosphorylation
          positive regulation of B cell activation
          positive regulation of immunoglobulin secretion
          positive regulation of sequence-specific DNA binding transcription factor activity
          response to glucocorticoid
          defense response to virus
          positive regulation of protein kinase B signaling
          positive regulation of transmission of nerve impulse
          branching involved in salivary gland morphogenesis
          epithelial cell proliferation involved in salivary gland morphogenesis
          glucagon secretion
          interleukin-6-mediated signaling pathway
          cellular response to hydrogen peroxide
          positive regulation of ERK1 and ERK2 cascade
          cellular response to lipopolysaccharide
          cellular response to interleukin-1
          cellular response to tumor necrosis factor
          T-helper 17 cell lineage commitment
          negative regulation of neuron death
          receptor binding
          cytokine activity
          interleukin-6 receptor binding
          protein binding
          growth factor activity

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          Citations (74)

          Parathyroid hormone-related protein promotes inflammation in the kidney with an obstructed ureter.
          Authors
          Ramila D, Ardura JA, Esteban V, Ortega A, Ruiz-Ortega M, Bosch RJ, Esbrit P
          Journal
          Kidney Int - Page No 835 (Tue Apr 01 00:00:00 EDT 2008)
          Volume (Year)
          73 (2008)
          Product Usage
          -
          Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance.
          Authors
          Tsukumo DM, Carvalho-Filho MA, Carvalheira JB, Prada PO, Hirabara SM, Schenka AA, Araujo EP, Vassallo J, Curi R, Velloso LA, Saad MJ
          Journal
          Diabetes - Page No 1986 (Wed Aug 01 00:00:00 EDT 2007)
          Volume (Year)
          56 (2007)
          Product Usage
          -
          Butter feeding enhances TNF-alpha production from macrophages and lymphocyte adherence in murine small intestinal microvessels.
          Authors
          Fujiyama Y, Hokari R, Miura S, Watanabe C, Komoto S, Oyama T, Kurihara C, Nagata H, Hibi T
          Journal
          J Gastroenterol Hepatol - Page No 1838 (Thu Nov 01 00:00:00 EDT 2007)
          Volume (Year)
          22 (2007)
          Product Usage
          -
          Fucoxanthin regulates adipocytokine mRNA expression in white adipose tissue of diabetic/obese KK-Ay mice.
          Authors
          Hosokawa M, Miyashita T, Nishikawa S, Emi S, Tsukui T, Beppu F, Okada T, Miyashita K
          Journal
          Arch Biochem Biophys - Page No 17 (Wed Dec 01 00:00:00 EST 2010)
          Volume (Year)
          504 (2010)
          Product Usage
          -
          Role of the C5a receptor (C5aR) in acute and chronic dextran sulfate-induced models of inflammatory bowel disease.
          Authors
          Johswich K, Martin M, Bleich A, Kracht M, Dittrich-Breiholz O, Gessner JE, Suerbaum S, Wende E, Rheinheimer C, Klos A
          Journal
          Inflamm Bowel Dis - Page No 1812 (Thu Aug 27 00:00:00 EDT 2009)
          Volume (Year)
          15 (2009)
          Product Usage
          -
          Active immunization with amyloid-beta 1-42 impairs memory performance through TLR2/4-dependent activation of the innate immune system.
          Authors
          Vollmar P, Kullmann JS, Thilo B, Claussen MC, Rothhammer V, Jacobi H, Sellner J, Nessler S, Korn T, Hemmer B
          Journal
          J Immunol - Page No 6338 (Mon Nov 15 00:00:00 EST 2010)
          Volume (Year)
          185 (2010)
          Product Usage
          -
          Echinostoma caproni (Trematoda): Differential in vivo cytokine responses in high and low compatible hosts.
          Authors
          Trelis M, Sotillo J, Monteagudo C, Fried B, Marcilla A, Esteban JG, Toledo R
          Journal
          Exp Parasitol - Page No (Thu Sep 16 00:00:00 EDT 2010)
          Volume (Year)
           (2010)
          Product Usage
          -
          Deletion of bradykinin B1 receptor reduces renal fibrosis.
          Authors
          Wang PH, Cenedeze MA, Campanholle G, Malheiros DM, Torres HA, Pesquero JB, Pacheco-Silva A, Camara NO
          Journal
          Int Immunopharmacol - Page No 653 (Mon Jun 01 00:00:00 EDT 2009)
          Volume (Year)
          9 (2009)
          Product Usage
          -
          Sickness behavior induced by endotoxin can be mitigated by the dietary soluble fiber, pectin, through up-regulation of IL-4 and Th2 polarization.
          Authors
          Sherry CL, Kim SS, Dilger RN, Bauer LL, Moon ML, Tapping RI, Fahey GC Jr, Tappenden KA, Freund GG
          Journal
          Brain Behav Immun - Page No 631 (Sat May 01 00:00:00 EDT 2010)
          Volume (Year)
          24 (2010)
          Product Usage
          -
          Uncoupling of inflammation and insulin resistance by NF-kappaB in transgenic mice through elevated energy expenditure.
          Authors
          Tang T, Zhang J, Yin J, Staszkiewicz J, Gawronska-Kozak B, Jung DY, Ko HJ, Ong H, Kim JK, Mynatt R, Martin RJ, Keenan M, Gao Z, Ye J
          Journal
          J Biol Chem - Page No 4637 (Fri Feb 12 00:00:00 EST 2010)
          Volume (Year)
          285 (2010)
          Product Usage
          -
          Pulmonary inflammation and tumor induction in lung tumor susceptible A/J and resistant C57BL/6J mice exposed to welding fume.
          Authors
          Zeidler-Erdely PC, Kashon ML, Battelli LA, Young SH, Erdely A, Roberts JR, Reynolds SH, Antonini JM
          Journal
          Part Fibre Toxicol - Page No 12 (Tue Jan 01 00:00:00 EST 2008)
          Volume (Year)
          5 (2008)
          Product Usage
          -
          Autoimmunity in dry eye is due to resistance of Th17 to Treg suppression.
          Authors
          Chauhan SK, El Annan J, Ecoiffier T, Goyal S, Zhang Q, Saban DR, Dana R
          Journal
          J Immunol - Page No 1247 (Sun Feb 01 00:00:00 EST 2009)
          Volume (Year)
          182 (2009)
          Product Usage
          -
          Schistosoma mansoni infection reduces severity of collagen-induced arthritis via down-regulation of pro-inflammatory mediators.
          Authors
          Osada Y, Shimizu S, Kumagai T, Yamada S, Kanazawa T
          Journal
          Int J Parasitol - Page No 457 (Sun Mar 01 00:00:00 EST 2009)
          Volume (Year)
          39 (2009)
          Product Usage
          -
          Age-dependent retinal iron accumulation and degeneration in Hepcidin knockout mice.
          Authors
          Hadziahmetovic M, Song Y, Ponnuru P, Iacovelli J, Hunter A, Haddad N, Beard J, Connor JR, Vaulont S, Dunaief J
          Journal
          Invest Ophthalmol Vis Sci - Page No (Wed Sep 01 00:00:00 EDT 2010)
          Volume (Year)
           (2010)
          Product Usage
          -
          Improved insulin sensitivity in high fat- and high cholesterol-fed Ldlr-/- mice with macrophage-specific transgenic expression of cholesteryl ester hydrolase: role of macrophage inflammation and infiltration into adipose tissue.
          Authors
          Bie J, Zhao B, Song J, Ghosh S
          Journal
          J Biol Chem - Page No 13630 (Fri Apr 30 00:00:00 EDT 2010)
          Volume (Year)
          285 (2010)
          Product Usage
          -
          Increased expression of cathepsins and obesity-induced proinflammatory cytokines in lacrimal glands of male NOD mouse.
          Authors
          Li X, Wu K, Edman M, Schenke-Layland K, MacVeigh-Aloni M, Janga SR, Schulz B, Hamm-Alvarez SF
          Journal
          Invest Ophthalmol Vis Sci - Page No 5019 (Fri Oct 01 00:00:00 EDT 2010)
          Volume (Year)
          51 (2010)
          Product Usage
          -
          Central administration of lipopolysaccharide induces depressive-like behavior in vivo and activates brain indoleamine 2,3 dioxygenase in murine organotypic hippocampal slice cultures.
          Authors
          Fu X, Zunich SM, O'Connor JC, Kavelaars A, Dantzer R, Kelley KW
          Journal
          J Neuroinflammation - Page No 43 (Fri Jan 01 00:00:00 EST 2010)
          Volume (Year)
          7 (2010)
          Product Usage
          -
          Luteolin reduces IL-6 production in microglia by inhibiting JNK phosphorylation and activation of AP-1.
          Authors
          Jang S, Kelley KW, Johnson RW
          Journal
          Proc Natl Acad Sci U S A - Page No 7534 (Tue May 27 00:00:00 EDT 2008)
          Volume (Year)
          105 (2008)
          Product Usage
          -
          Mechanisms of sex differences in TNFR2-mediated cardioprotection.
          Authors
          Wang M, Crisostomo PR, Markel TA, Wang Y, Meldrum DR
          Journal
          Circulation - Page No S38 (Tue Sep 30 00:00:00 EDT 2008)
          Volume (Year)
          118 (2008)
          Product Usage
          -
          Cognitive and neuroinflammatory consequences of mild repeated stress are exacerbated in aged mice.
          Authors
          Buchanan JB, Sparkman NL, Chen J, Johnson RW
          Journal
          Psychoneuroendocrinology - Page No 755 (Tue Jul 01 00:00:00 EDT 2008)
          Volume (Year)
          33 (2008)
          Product Usage
          -
          Mutant alpha-synuclein overexpression mediates early proinflammatory activity.
          Authors
          Su X, Federoff HJ, Maguire-Zeiss KA
          Journal
          Neurotox Res - Page No 238 (Thu Oct 01 00:00:00 EDT 2009)
          Volume (Year)
          16 (2009)
          Product Usage
          -
          Overexpression of human S100B exacerbates cerebral amyloidosis and gliosis in the Tg2576 mouse model of Alzheimer's disease.
          Authors
          Mori T, Koyama N, Arendash GW, Horikoshi-Sakuraba Y, Tan J, Town T
          Journal
          Glia - Page No 300 (Mon Feb 01 00:00:00 EST 2010)
          Volume (Year)
          58 (2010)
          Product Usage
          -
          Differential effects of rapamycin in anti-GBM glomerulonephritis.
          Authors
          Hochegger K, Jansky GL, Soleiman A, Wolf AM, Tagwerker A, Seger C, Griesmacher A, Mayer G, Rosenkranz AR
          Journal
          J Am Soc Nephrol - Page No 1520 (Fri Aug 01 00:00:00 EDT 2008)
          Volume (Year)
          19 (2008)
          Product Usage
          -
          Kupffer cell-dependent TNF-alpha signaling mediates injury in the arterialized small-for-size liver transplantation in the mouse.
          Authors
          Tian Y, Jochum W, Georgiev P, Moritz W, Graf R, Clavien PA
          Journal
          Proc Natl Acad Sci U S A - Page No 4598 (Tue Mar 21 00:00:00 EST 2006)
          Volume (Year)
          103 (2006)
          Product Usage
          -
          Interferon-gamma treatment accelerates and aggravates autoimmune pancreatitis in the MRL/Mp-mouse.
          Authors
          Fitzner B, Holzhueter SA, Ibrahim S, Nizze H, Jaster R
          Journal
          Pancreatology - Page No 233 (Thu Jan 01 00:00:00 EST 2009)
          Volume (Year)
          9 (2009)
          Product Usage
          -
          Neuroinflammation and disruption in working memory in aged mice after acute stimulation of the peripheral innate immune system.
          Authors
          Chen J, Buchanan JB, Sparkman NL, Godbout JP, Freund GG, Johnson RW
          Journal
          Brain Behav Immun - Page No 301 (Sat Mar 01 00:00:00 EST 2008)
          Volume (Year)
          22 (2008)
          Product Usage
          -
          Atorvastatin attenuates murine anti-glomerular basement membrane glomerulonephritis.
          Authors
          Eller P, Eller K, Wolf AM, Reinstadler SJ, Tagwerker A, Patsch JR, Mayer G, Rosenkranz AR
          Journal
          Kidney Int - Page No 428 (Mon Mar 01 00:00:00 EST 2010)
          Volume (Year)
          77 (2010)
          Product Usage
          -
          Staphylococcus Aureus Sepsis and Mitochondrial Accrual of OGG1 DNA Repair Enzyme in Mice.
          Authors
          Bartz RR, Suliman HB, Fu P, Welty-Wolf K, Carraway MS, Macgarvey NC, Withers CM, Sweeney TE, Piantadosi CA
          Journal
          Am J Respir Crit Care Med - Page No (Mon Aug 23 00:00:00 EDT 2010)
          Volume (Year)
           (2010)
          Product Usage
          -
          Suppressive effects of alloxanthin and diatoxanthin from Halocynthia roretzi on LPS-induced expression of pro-inflammatory genes in RAW264.7 cells.
          Authors
          Konishi I, Hosokawa M, Sashima T, Maoka T, Miyashita K
          Journal
          J Oleo Sci - Page No 181 (Tue Jan 01 00:00:00 EST 2008)
          Volume (Year)
          57 (2008)
          Product Usage
          -
          Endogenous interleukin-10 inhibits angiotensin II-induced vascular dysfunction.
          Authors
          Didion SP, Kinzenbaw DA, Schrader LI, Chu Y, Faraci FM
          Journal
          Hypertension - Page No 619 (Tue Sep 01 00:00:00 EDT 2009)
          Volume (Year)
          54 (2009)
          Product Usage
          -
          Apelin prevents aortic aneurysm formation by inhibiting macrophage inflammation.
          Authors
          Leeper NJ, Tedesco MM, Kojima Y, Schultz GM, Kundu RK, Ashley EA, Tsao PS, Dalman RL, Quertermous T
          Journal
          Am J Physiol Heart Circ Physiol - Page No H1329 (Fri May 01 00:00:00 EDT 2009)
          Volume (Year)
          296 (2009)
          Product Usage
          -
          Peripheral lipopolysaccharide administration induces cytokine mRNA expression in the viscera and brain of fever-refractory mice lacking microsomal prostaglandin E synthase-1.
          Authors
          Nilsberth C, Hamzic N, Norell M, Blomqvist A
          Journal
          J Neuroendocrinol - Page No 715 (Sat Aug 01 00:00:00 EDT 2009)
          Volume (Year)
          21 (2009)
          Product Usage
          -
          TLR4 activation mediates kidney ischemia/reperfusion injury.
          Authors
          Wu H, Chen G, Wyburn KR, Yin J, Bertolino P, Eris JM, Alexander SI, Sharland AF, Chadban SJ
          Journal
          J Clin Invest - Page No 2847 (Mon Oct 01 00:00:00 EDT 2007)
          Volume (Year)
          117 (2007)
          Product Usage
          -
          Cognitive deficits in interleukin-10-deficient mice after peripheral injection of lipopolysaccharide.
          Authors
          Richwine AF, Sparkman NL, Dilger RN, Buchanan JB, Johnson RW
          Journal
          Brain Behav Immun - Page No 794 (Sat Aug 01 00:00:00 EDT 2009)
          Volume (Year)
          23 (2009)
          Product Usage
          -
          Proinflammatory role of the Th17 cytokine interleukin-22 in collagen-induced arthritis in C57BL/6 mice.
          Authors
          Geboes L, Dumoutier L, Kelchtermans H, Schurgers E, Mitera T, Renauld JC, Matthys P
          Journal
          Arthritis Rheum - Page No 390 (Sun Feb 01 00:00:00 EST 2009)
          Volume (Year)
          60 (2009)
          Product Usage
          -
          Orally administered lactoperoxidase ameliorates dextran sulfate sodium-induced colitis in mice by up-regulating colonic interleukin-10 and maintaining peripheral regulatory T cells.
          Authors
          Shin K, Horigome A, Yamauchi K, Yaeshima T, Iwatsuki K
          Journal
          Int Immunopharmacol - Page No 1387 (Sun Nov 01 00:00:00 EDT 2009)
          Volume (Year)
          9 (2009)
          Product Usage
          -
          Interleukin-6 facilitates lipopolysaccharide-induced disruption in working memory and expression of other proinflammatory cytokines in hippocampal neuronal cell layers.
          Authors
          Sparkman NL, Buchanan JB, Heyen JR, Chen J, Beverly JL, Johnson RW
          Journal
          J Neurosci - Page No 10709 (Wed Oct 18 00:00:00 EDT 2006)
          Volume (Year)
          26 (2006)
          Product Usage
          -
          Modulation of acute diarrheal illness by persistent bacterial infection.
          Authors
          McBee ME, Zheng PZ, Rogers AB, Fox JG, Schauer DB
          Journal
          Infect Immun - Page No 4851 (Sat Nov 01 00:00:00 EDT 2008)
          Volume (Year)
          76 (2008)
          Product Usage
          -
          Site-specific inhibition of glomerulonephritis progression by targeted delivery of dexamethasone to glomerular endothelium.
          Authors
          Asgeirsdottir SA, Kamps JA, Bakker HI, Zwiers PJ, Heeringa P, van der Weide K, van Goor H, Petersen AH, Morselt H, Moorlag HE, Steenbergen E, Kallenberg CG, Molema G
          Journal
          Mol Pharmacol - Page No 121 (Sun Jul 01 00:00:00 EDT 2007)
          Volume (Year)
          72 (2007)
          Product Usage
          -
          Purple carrot (Daucus carota L.) polyacetylenes decrease lipopolysaccharide-induced expression of inflammatory proteins in macrophage and endothelial cells.
          Authors
          Metzger BT, Barnes DM, Reed JD
          Journal
          J Agric Food Chem - Page No 3554 (Wed May 28 00:00:00 EDT 2008)
          Volume (Year)
          56 (2008)
          Product Usage
          -
          Both TLR2 and TLR4 are required for the effective immune response in Staphylococcus aureus-induced experimental murine brain abscess.
          Authors
          Stenzel W, Soltek S, Sanchez-Ruiz M, Akira S, Miletic H, Schluter D, Deckert M
          Journal
          Am J Pathol - Page No 132 (Tue Jan 01 00:00:00 EST 2008)
          Volume (Year)
          172 (2008)
          Product Usage
          -
          Interleukin-10 overexpression promotes Fas-ligand-dependent chronic macrophage-mediated demyelinating polyneuropathy.
          Authors
          Dace DS, Khan AA, Stark JL, Kelly J, Cross AH, Apte RS
          Journal
          Plos One - Page No e7121 (Thu Jan 01 00:00:00 EST 2009)
          Volume (Year)
          4 (2009)
          Product Usage
          -
          Melanoma differentiation-associated gene 5 (MDA5) is involved in the innate immune response to Paramyxoviridae infection in vivo.
          Authors
          Gitlin L, Benoit L, Song C, Cella M, Gilfillan S, Holtzman MJ, Colonna M
          Journal
          Plos Pathog - Page No e1000734 (Fri Jan 01 00:00:00 EST 2010)
          Volume (Year)
          6 (2010)
          Product Usage
          -
          Topical delivery of silver nanoparticles promotes wound healing.
          Authors
          Tian J, Wong KK, Ho CM, Lok CN, Yu WY, Che CM, Chiu JF, Tam PK
          Journal
          Chemmedchem - Page No 129 (Mon Jan 01 00:00:00 EST 2007)
          Volume (Year)
          2 (2007)
          Product Usage
          -
          The purinergic antagonist PPADS reduces pain related behaviours and interleukin-1 beta, interleukin-6, iNOS and nNOS overproduction in central and peripheral nervous system after peripheral neuropathy in mice.
          Authors
          Martucci C, Trovato AE, Costa B, Borsani E, Franchi S, Magnaghi V, Panerai AE, Rodella LF, Valsecchi AE, Sacerdote P, Colleoni M
          Journal
          Pain - Page No 81 (Tue Jul 01 00:00:00 EDT 2008)
          Volume (Year)
          137 (2008)
          Product Usage
          -
          Early rise in inflammation and microcirculatory disorder determine the development of autoimmune pancreatitis in the MRL/Mp-mouse.
          Authors
          Sorg H, Lorch B, Jaster R, Fitzner B, Ibrahim S, Holzhueter SA, Nizze H, Vollmar B
          Journal
          Am J Physiol Gastrointest Liver Physiol - Page No G1274 (Mon Dec 01 00:00:00 EST 2008)
          Volume (Year)
          295 (2008)
          Product Usage
          -
          Bacterial lipopeptide triggers massive albuminuria in murine lupus nephritis by activating Toll-like receptor 2 at the glomerular filtration barrier.
          Authors
          Pawar RD, Castrezana-Lopez L, Allam R, Kulkarni OP, Segerer S, Radomska E, Meyer TN, Schwesinger CM, Akis N, Grone HJ, Anders HJ
          Journal
          Immunology - Page No e206 (Tue Sep 01 00:00:00 EDT 2009)
          Volume (Year)
          128 (2009)
          Product Usage
          -
          Fumonisin B1-induced neurodegeneration in mice after intracerebroventricular infusion is concurrent with disruption of sphingolipid metabolism and activation of proinflammatory signaling.
          Authors
          Osuchowski MF, Edwards GL, Sharma RP
          Journal
          Neurotoxicology - Page No 211 (Tue Mar 01 00:00:00 EST 2005)
          Volume (Year)
          26 (2005)
          Product Usage
          -
          Psychological stress reactivates dextran sulfate sodium-induced chronic colitis in mice.
          Authors
          Melgar S, Engstrom K, Jagervall A, Martinez V
          Journal
          Stress - Page No 348 (Tue Jan 01 00:00:00 EST 2008)
          Volume (Year)
          11 (2008)
          Product Usage
          -
          Vascular cellular adhesion molecule-1 (VCAM-1) expression in mice retinal vessels is affected by both hyperglycemia and hyperlipidemia.
          Authors
          Gustavsson C, Agardh CD, Zetterqvist AV, Nilsson J, Agardh E, Gomez MF
          Journal
          Plos One - Page No e12699 (Fri Jan 01 00:00:00 EST 2010)
          Volume (Year)
          5 (2010)
          Product Usage
          -
          alpha-Tocopherol and selenium facilitate recovery from lipopolysaccharide-induced sickness in aged mice.
          Authors
          Berg BM, Godbout JP, Chen J, Kelley KW, Johnson RW
          Journal
          J Nutr - Page No 1157 (Sun May 01 00:00:00 EDT 2005)
          Volume (Year)
          135 (2005)
          Product Usage
          -
          Architectural changes to CA1 pyramidal neurons in adult and aged mice after peripheral immune stimulation.
          Authors
          Richwine AF, Parkin AO, Buchanan JB, Chen J, Markham JA, Juraska JM, Johnson RW
          Journal
          Psychoneuroendocrinology - Page No 1369 (Sat Nov 01 00:00:00 EDT 2008)
          Volume (Year)
          33 (2008)
          Product Usage
          -
          Senescence regulates macrophage activation and angiogenic fate at sites of tissue injury in mice.
          Authors
          Kelly J, Ali Khan A, Yin J, Ferguson TA, Apte RS
          Journal
          J Clin Invest - Page No 3421 (Thu Nov 01 00:00:00 EDT 2007)
          Volume (Year)
          117 (2007)
          Product Usage
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          Choosing the frequency of deep inflation in mice: balancing recruitment against ventilator-induced lung injury.
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          Allen GB, Suratt BT, Rinaldi L, Petty JM, Bates JH
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          Endothelial CYP epoxygenase overexpression and soluble epoxide hydrolase disruption attenuate acute vascular inflammatory responses in mice.
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          Nasal vaccination with troponin reduces troponin specific T-cell responses and improves heart function in myocardial ischemia-reperfusion injury.
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          Frenkel D, Pachori AS, Zhang L, Dembinsky-Vaknin A, Farfara D, Petrovic-Stojkovic S, Dzau VJ, Weiner HL
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          Stenzel W, Dahm J, Sanchez-Ruiz M, Miletic H, Hermann M, Courts C, Schwindt H, Utermohlen O, Schluter D, Deckert M
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          Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens.
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          Lech M, Kulkarni OP, Pfeiffer S, Savarese E, Krug A, Garlanda C, Mantovani A, Anders HJ
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          Kelchtermans H, Schurgers E, Geboes L, Mitera T, Van Damme J, Van Snick J, Uyttenhove C, Matthys P
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          11 (2009)
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          Angiotensin-(1-7) and the g protein-coupled receptor MAS are key players in renal inflammation.
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          Veldhoen M, Moncrieffe H, Hocking RJ, Atkins CJ, Stockinger B
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          8 (2008)
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          Petrzilka S, Taraborrelli C, Cavadini G, Fontana A, Birchler T
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          24 (2009)
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          Miyatake K, Inoue H, Hashimoto K, Takaku H, Takata Y, Nakano S, Yasui N, Itakura M
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          360 (2007)
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          Topical omega-3 and omega-6 fatty acids for treatment of dry eye.
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          Rashid S, Jin Y, Ecoiffier T, Barabino S, Schaumberg DA, Dana MR
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          126 (2008)
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          IL-9 Production by Regulatory T Cells Recruits Mast Cells That Are Essential for Regulatory T Cell-Induced Immune Suppression.
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          Eller K, Wolf D, Huber JM, Metz M, Mayer G, McKenzie AN, Maurer M, Rosenkranz AR, Wolf AM
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           (2010)
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          Intra-colonic administration of the TLR7 agonist R-848 induces an acute local and systemic inflammation in mice.
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          Karlsson A, Jagervall K, Utkovic H, Karlsson L, Rehnstrom E, Fredin MF, Gillberg PG, Jansson L, Michaelsson E, Melgar S
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          367 (2008)
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          Aging sensitizes mice to behavioral deficits induced by central HIV-1 gp120.
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          29 (2008)
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          Inactivation of NF-kappaB p50 leads to insulin sensitization in liver through post-translational inhibition of p70S6K.
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          Gao Z, Yin J, Zhang J, He Q, McGuinness OP, Ye J
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          284 (2009)
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          Suppression of proinflammatory cytokine production in macrophages by lansoprazole.
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          22 (2006)
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          -
          Subtherapeutic dose of pioglitazone reduces expression of inflammatory adipokines in db/db mice.
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          84 (2009)
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          Vollmar P, Nessler S, Kalluri SR, Hartung HP, Hemmer B
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          Volume (Year)
          12 (2009)
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