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          • › Search Tool
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          • › Rn00580555_m1
          See other CCL2 GE Assays ›
          Gene Symbol:
          Ccl2
          Gene Name:
          chemokine (C-C motif) ligand 2
          Gene Aliases:
          MCP-1, Scya2, Sigje
          Chromosome Location:
          Chr.10: 69412065 - 69413863 on Build Rnor_6.0
          Species:
          Rat
          Species Specific ID (Flybase ID):
          -
          Assay ID Rn00580555_m1
          Best Coverage
          Size
          Availability Inventoried
          Catalog # 4331182
          Price
          Your Price
          Online offer:
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          • Genomic Map
          • Assay Details
          • More Information
          • Citations (3)

          Genomic Map

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          Assay Details

          Gene Symbol: Ccl2
          Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
          RefSeq NM_031530.1 NP_113718.1 1 - 2 155 95
          GenBank mRNA AF058786.1 - 1 - 2 155 95
          M57441.1 - 1 - 2 119 95

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          More Information


          Updated Mapping Information

          This assay targets the same location as RTA transcript cluster(s) TC1000001226.rn.1

          Set Membership:

          Ambion siRNA available Amplicon length between 86 and 100 Recommended Assay Rattus norvegicus Rat Chemokine Panel Rat Tumor Metastasis Panel Inventoried Probe spans exons

          Matching Ambion siRNAs:

          Click here to find siRNAs for Gene Ccl2

          Panther Classification:

          Molecular Function -

          cytokine intercellular signal molecule

          Gene Ontology Categories:

          Function(s) Process(es)

          MAPK cascade
          response to hypoxia
          positive regulation of leukocyte mediated cytotoxicity
          positive regulation of endothelial cell proliferation
          leukocyte migration involved in inflammatory response
          monocyte chemotaxis
          positive regulation of leukocyte migration
          positive regulation of cellular extravasation
          cellular calcium ion homeostasis
          inflammatory response
          cytoskeleton organization
          transforming growth factor beta receptor signaling pathway
          aging
          glial cell migration
          regulation of cell shape
          response to heat
          response to wounding
          response to mechanical stimulus
          response to bacterium
          response to gamma radiation
          regulation of vascular endothelial growth factor production
          positive regulation of macrophage chemotaxis
          response to activity
          negative regulation of angiogenesis
          cytokine-mediated signaling pathway
          positive regulation of cell-cell adhesion
          neutrophil chemotaxis
          organ regeneration
          lipopolysaccharide-mediated signaling pathway
          response to lipopolysaccharide
          response to progesterone
          positive regulation of tumor necrosis factor production
          cellular response to insulin stimulus
          positive regulation of collagen biosynthetic process
          response to vitamin B3
          negative regulation of glial cell apoptotic process
          helper T cell extravasation
          cellular response to drug
          cellular response to macrophage colony-stimulating factor stimulus
          cellular response to platelet-derived growth factor stimulus
          chemokinesis
          response to drug
          response to amino acid
          protein kinase B signaling
          negative regulation of neuron apoptotic process
          astrocyte cell migration
          cellular response to fibroblast growth factor stimulus
          response to ethanol
          positive regulation of cell adhesion
          response to antibiotic
          vascular endothelial growth factor receptor signaling pathway
          macrophage chemotaxis
          lymphocyte chemotaxis
          positive regulation of synaptic transmission
          positive regulation of T cell activation
          response to glucocorticoid
          positive regulation of nitric-oxide synthase biosynthetic process
          maternal process involved in female pregnancy
          maternal process involved in parturition
          chemokine-mediated signaling pathway
          cellular response to lipopolysaccharide
          cellular response to retinoic acid
          cellular response to ATP
          cellular response to interferon-gamma
          cellular response to interleukin-1
          cellular response to interleukin-6
          cellular response to tumor necrosis factor
          cellular response to lipoprotein particle stimulus
          cellular response to high density lipoprotein particle stimulus
          cellular response to organic cyclic compound
          cellular response to dexamethasone stimulus
          positive regulation of monocyte chemotaxis
          positive regulation of immune complex clearance by monocytes and macrophages
          positive regulation of calcium ion import
          positive regulation of protein targeting to membrane
          positive regulation of apoptotic cell clearance
          negative regulation of natural killer cell chemotaxis
          G-protein coupled receptor binding
          chemokine activity
          heparin binding
          CCR2 chemokine receptor binding

          MicroArray Probes:

          Affymetrix

          Array Name Probe IDs Targets Target Type
          Affymetrix Rat Clariom S Assay PSR1000011219.rn.1 TC1000001226.rn.1 RTA TC
          Affymetrix Rat Clariom S Assay PSR1000011220.rn.1 TC1000001226.rn.1 RTA TC

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          Citations (3)

          SOCS3-mediated blockade of JAK/STAT3 signaling pathway reveals its major contribution to spinal cord neuroinflammation and mechanical allodynia after peripheral nerve injury.
          Authors
          Dominguez E, Mauborgne A, Mallet J, Desclaux M, Pohl M
          Journal
          J Neurosci - Page No 5754 (Wed Apr 21 00:00:00 EDT 2010)
          Volume (Year)
          30 (2010)
          Product Usage
          -
          Effects of a new bioactive lipid-based drug carrier on cultured hepatic stellate cells and liver fibrosis in bile duct-ligated rats.
          Authors
          Adrian JE, Poelstra K, Scherphof GL, Meijer DK, van Loenen-Weemaes AM, Reker-Smit C, Morselt HW, Zwiers P, Kamps JA
          Journal
          J Pharmacol Exp Ther - Page No 536 (Tue May 01 00:00:00 EDT 2007)
          Volume (Year)
          321 (2007)
          Product Usage
          -
          Early postnatal oestradiol exposure causes insulin resistance and signs of inflammation in circulation and skeletal muscle.
          Authors
          Alexanderson C, Eriksson E, Stener-Victorin E, Lonn M, Holmang A
          Journal
          J Endocrinol - Page No 49 (Wed Apr 01 00:00:00 EDT 2009)
          Volume (Year)
          201 (2009)
          Product Usage
          -

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