ATM Antibodies

Antibodies that detect ATM can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target ATM in Human, Mouse, Rat, Canine and Marsupial samples. Our ATM polyclonal, monoclonal... Antibodies that detect ATM can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target ATM in Human, Mouse, Rat, Canine and Marsupial samples. Our ATM polyclonal, monoclonal and recombinant monoclonal... Antibodies that detect ATM can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target ATM in Human, Mouse, Rat, Canine and Marsupial samples. Our ATM polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse, Goat and Sheep. These antibodies have been verified by Knockout, Knockdown, Cell treatment and Relative expression to confirm specificity to ATM. Find the ATM antibody that fits your needs. Choose from 1 of 74 ATM antibodies, which have been validated in experiments with 53 publications and 191 images featured in our data gallery.

Browse primary antibodies for WB, Flow,... Antibodies that detect ATM can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target ATM in Human, Mouse, Rat, Canine and Marsupial samples. Our ATM polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse, Goat and Sheep. These antibodies have been verified by Knockout, Knockdown, Cell treatment and Relative expression to confirm specificity to ATM. Find the ATM antibody that fits your needs. Choose from 1 of 74 ATM antibodies, which have been validated in experiments with 53 publications and 191 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

Ataxia-telangiectasia Mutated (ATM) is a protein that belongs to the PI3/PI4 kinase family. Ataxia-telangiectasia is a rare autosomal recessive disorder characterized by progressive neurologic degeneration, immunologic deficiency, and an increased risk of lymphoid cancer. The ATM gene codes for a protein belonging to the phosphoinositide 3-kinase (PI3K) superfamily. ATM phosphorylates proteins instead of lipid and has many downstream targets that act as cell-cycle regulators including: P53, Mdm2, BRCA1, and SMC1. The ATM protein is responsible for repairing double-stranded DNA breaks that occur because of ionizing radiation and other mutagens. The ATM¿s C-terminal region has extensive homology to the catalytic domains of phosphatidylinositol 3-kinases (PI3 kinases). Studies have shown that ATM becomes autophosphorylated and upregulated by exposure to ionizing radiation. AT cells are hypersensitive to ionizing radiation, impaired in mediating the inhibition of DNA synthesis and display delays in p53 induction. Further, DNA damage caused by ionizing irradiation activates ATM-kinase, leading to a cascade of kinase reactions that regulate cell cycle, apoptosis, and DNA damage repair. Studies have linked ATM to apoptosis along with Nbs1 and Chk2 in the E2F1 pathway.

Synonyms

AI256621; AT mutated; A-T mutated; A-T mutated homolog; AT mutated protein; AT1; ATA; Ataxia t; Ataxia telangiectasia gene mutated in human beings; ataxia telangiectasia mutated; Ataxia telangiectasia mutated homolog; ATC; ATD; ATDC; ATE; Atm; ATM serine/threonine kinase; C030026E19Rik; DKFZp781A0353; EC 2.7.1.37; MGC74674; serine-protein kinase ATM; TEL1; TEL1, telomere maintenance 1, homolog; TELO1

Target Video

6320245768112

ATM antibodies from Thermo Fisher Scientific

https://cf-images.us-east-1.prod.boltdns.net/v1/static/3663210762001/4d95b5a0-e026-4b12-82a2-db5d6c290986/6cf9176a-32d7-4a10-89db-add90b9ca4f5/320x180/match/image.jpg

Learn more about ATM primary antibodies that can be used in Western Blot, Immunohistochemistry, Immunocytochemistry and Immunoprecipitation in Human, Mouse, Rat and Dog samples.

atm

PT0M37S

2023-02-12T10:48:06.939Z

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ATM Antibodies

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