Cytokeratin 10/14/17/19/42 Antibodies

Target Information

The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.This gene encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. [provided by RefSeq, Aug 2008].

Synonyms

39.1; 40-kDa keratin intermediate filament; 56 kDa cytokeratin; AI626930; AI663979; BCIE; BIE; CK10; CK-10; CK14; CK-14; CK-17; CK19; CK-19; cytokeratin 10; cytokeratin 14; cytokeratin 19; cytokeratin-10; Cytokeratin-14; cytokeratin-17; Cytokeratin-19; D130054E02Rik; EBS3; EBS4; EHK; EndoC; epidermal keratin 10; epidermolysis bullosa simplex, Dowling-Meara, Koebner; intermediate filament protein; K10; K14; K17; K19; K1C1; K1CS; Ka10; Ka14; Ka17; Ka19; keratin 10; keratin 10, type I; keratin 14; keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner); keratin 14, type I; keratin 17; keratin 17, type I; keratin 19; keratin 19, type I; keratin complex 1, acidic, gene 10; keratin complex 1, acidic, gene 14; keratin complex 1, acidic, gene 17; keratin complex 1, acidic, gene 19; keratin, type I cytoskeletal 10; Keratin, type I cytoskeletal 14; keratin, type I cytoskeletal 17; Keratin, type I cytoskeletal 19; keratin, type I cytoskeletal 59 kDa; keratin, type I, 40-kd; keratin-10; Keratin-14; keratin-17; Keratin-19; KPP; Krt-1.10; Krt-1.14; Krt-1.19; KRT10; krt10 {ECO:0000250; Krt1-10; Krt1-14; Krt1-17; Krt1-19; Krt14; Krt17; krt17 {ECO:0000250; KRT19; NFJ; PC; PC2; PCHC1; suprabasal cytokeratin 10; type I keratin KA10; Type I keratin Ka14; type I keratin KA17; Type I keratin Ka19; UniProtKB:P13645}; UniProtKB:Q04695}