IRF3 Antibodies

Antibodies that detect IRF3 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, Flow Cytometry and Peptide array. These antibodies target IRF3 in Human, Mouse, Rat, Non-human primate and Bovine samples. Our IRF3 monoclonal,... Antibodies that detect IRF3 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, Flow Cytometry and Peptide array. These antibodies target IRF3 in Human, Mouse, Rat, Non-human primate and Bovine samples. Our IRF3 monoclonal, polyclonal, recombinant... Antibodies that detect IRF3 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, Flow Cytometry and Peptide array. These antibodies target IRF3 in Human, Mouse, Rat, Non-human primate and Bovine samples. Our IRF3 monoclonal, polyclonal, recombinant monoclonal and recombinant superclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Knockout, Knockdown, Cell treatment and Relative expression to confirm specificity to IRF3. Find the IRF3 antibody that fits your needs. Choose from 1 of 71 IRF3 antibodies, which have been validated in experiments with 189 publications and 262 images featured in our data gallery.

Browse primary... Antibodies that detect IRF3 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, Flow Cytometry and Peptide array. These antibodies target IRF3 in Human, Mouse, Rat, Non-human primate and Bovine samples. Our IRF3 monoclonal, polyclonal, recombinant monoclonal and recombinant superclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Knockout, Knockdown, Cell treatment and Relative expression to confirm specificity to IRF3. Find the IRF3 antibody that fits your needs. Choose from 1 of 71 IRF3 antibodies, which have been validated in experiments with 189 publications and 262 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

IFR3 (interferon regulatory factor 3) is a key transcriptional regulator of type I interferon (IFN)-dependent immune responses. It plays a critical role in the innate immune response against DNA and RNA viruses. IFR3 regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. It acts as a more potent activator of the IFN-beta gene than the IFN-alpha gene and plays a critical role in both the early and late phases of the IFNA/B gene induction. IFR3 is found in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA, or toll-like receptor signaling. It is phosphorylated by IKBKE and TBK1 kinases. This induces a conformational change, leading to its dimerization and nuclear localization and association with CREB binding protein to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of the type I IFN and ISG genes. Mutations in the gene can result in encephalopathy, acute, infection-induced, herpes-specific 7.

Synonyms

C920001K05Rik; IIAE7; Interferon regulatory factor 3; Irf3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3

Target Video

6320259365112

IRF3 antibodies from Thermo Fisher Scientific

https://cf-images.us-east-1.prod.boltdns.net/v1/static/3663210762001/e2816481-f5db-4aec-b633-d904ed597ecf/063be4b3-542d-4033-b809-f65c7d5687e7/160x90/match/image.jpg

Learn more about IRF3 primary antibodies that can be used in Western Blot, Immunocytochemistry, Immunohistochemistry and Flow Cytometry in Human, Mouse, Rat and Non-human primate samples.

irf3

PT0M32S

2023-02-12T15:39:41.586Z

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IRF3 Antibodies

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