MDMX Antibodies

Antibodies that detect MDMX can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA and Immunoprecipitation. These antibodies target MDMX in Human, Mouse and Rat samples. Our MDMX monoclonal, polyclonal and recombinant... Antibodies that detect MDMX can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA and Immunoprecipitation. These antibodies target MDMX in Human, Mouse and Rat samples. Our MDMX monoclonal, polyclonal and recombinant monoclonal antibodies are... Antibodies that detect MDMX can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA and Immunoprecipitation. These antibodies target MDMX in Human, Mouse and Rat samples. Our MDMX monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rabbit, Alpaca and Goat. Find the MDMX antibody that fits your needs. Choose from 1 of 54 MDMX antibodies, which have been validated in experiments with 30 publications and 144 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody... Antibodies that detect MDMX can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA and Immunoprecipitation. These antibodies target MDMX in Human, Mouse and Rat samples. Our MDMX monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rabbit, Alpaca and Goat. Find the MDMX antibody that fits your needs. Choose from 1 of 54 MDMX antibodies, which have been validated in experiments with 30 publications and 144 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

The MDM2 protein is the primary regulator of p53 protein stability. MDMX is an MDM2-related protein that inhibits MDM2-mediated degradation of p53 via distinct associations with MDM2. The gene that encodes MDMX (also designated MDM4) is a target for amplification in malignant gliomas. ARF interacts with MDMX to sequester MDMX within the nucleolus. This sequestration of MDMX by ARF results in an increase in p53 transactivation. In addition, expression of MDMX can reverse MDM2-targeted degradation of p53 while maintaining suppression of p53 transactivation. Like MDM2, MDMX also binds p73 and stabilizes the level of p73. Therefore, in striking contrast to p53, the half-life of p73 is increased by binding to MDM2.

Synonyms

4933417N07Rik; AA414968; AL023055; AU018793; AU021806; C85810; DKFZp781B1423; double minute 4 homolog; double minute 4 protein; double minute 4, human homolog of; p53-binding protein; HDMX; human homolog of; Mdm2-like p53-binding protein; MDM4; Mdm4 p53 binding protein homolog; MDM4 protein variant G; MDM4 protein variant Y; MDM4, p53 regulator; MDM4-related protein 1; Mdmx; MGC132766; MRP1; p53-binding protein Mdm4; protein Mdm4; Protein Mdmx; RP11-430C7.1; transformed mouse 3T3 cell double minute 4

Target Video

6320263069112

MDMX antibodies from Thermo Fisher Scientific

https://cf-images.us-east-1.prod.boltdns.net/v1/static/3663210762001/c5d7b535-a3e5-4390-a70c-6d32e662c164/c2a69019-c59f-46f0-a1bb-34b56a3333c8/320x180/match/image.jpg

Learn more about MDMX primary antibodies that can be used in Western Blot, Immunocytochemistry, Immunohistochemistry and Immunoprecipitation in Human, Mouse and Rat samples.

mdmx

PT0M37S

2023-02-12T16:12:37.631Z

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MDMX Antibodies

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