LAIR1 (CD305) Antibodies

Antibodies that detect LAIR1 (CD305) can be used in several scientific applications, including Western Blot, Flow Cytometry, Immunohistochemistry, Immunoprecipitation and ELISA. These antibodies target LAIR1 (CD305) in Human, Mouse and Rat samples. Our LAIR1 (CD305) monoclonal,... Antibodies that detect LAIR1 (CD305) can be used in several scientific applications, including Western Blot, Flow Cytometry, Immunohistochemistry, Immunoprecipitation and ELISA. These antibodies target LAIR1 (CD305) in Human, Mouse and Rat samples. Our LAIR1 (CD305) monoclonal, polyclonal and recombinant monoclonal... Antibodies that detect LAIR1 (CD305) can be used in several scientific applications, including Western Blot, Flow Cytometry, Immunohistochemistry, Immunoprecipitation and ELISA. These antibodies target LAIR1 (CD305) in Human, Mouse and Rat samples. Our LAIR1 (CD305) monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rabbit, Armenian Hamster and Goat. These antibodies have been verified by Relative expression to confirm specificity to LAIR1 (CD305). Find the LAIR1 (CD305) antibody that fits your needs. Choose from 1 of 29 LAIR1 (CD305) antibodies, which have been validated in experiments with 7 publications and 56 images featured in our data gallery.

Browse primary antibodies for WB, Flow,... Antibodies that detect LAIR1 (CD305) can be used in several scientific applications, including Western Blot, Flow Cytometry, Immunohistochemistry, Immunoprecipitation and ELISA. These antibodies target LAIR1 (CD305) in Human, Mouse and Rat samples. Our LAIR1 (CD305) monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rabbit, Armenian Hamster and Goat. These antibodies have been verified by Relative expression to confirm specificity to LAIR1 (CD305). Find the LAIR1 (CD305) antibody that fits your needs. Choose from 1 of 29 LAIR1 (CD305) antibodies, which have been validated in experiments with 7 publications and 56 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

LAIR1 (CD305) functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of intracellular calcium evoked by B-cell receptor ligation. May also play its inhibitory role independently of SH2-containing phosphatases. Modulates cytokine production in CD4+ T-cells, down-regulating IL2 and IFNG production while inducing secretion of transforming growth factor beta. Down-regulates also IgG and IgE production in B-cells as well as IL8, IL10 and TNF secretion. Inhibits proliferation and induces apoptosis in myeloid leukemia cell lines as well as prevents nuclear translocation of NF-kappa-B p65 subunit/RELA and phosphorylation of I-kappa-B alpha/CHUK in these cells. Inhibits the differentiation of peripheral blood precursors towards dendritic cells.

Synonyms

5133400O11Rik; BB115266; CD305; D7Bwg0421e; immunoglobulin heavy chain variable region; Lair1; LAIR-1; leukocyte associated immunoglobulin like receptor 1; leukocyte-associated Ig-like receptor 1; leukocyte-associated Ig-like receptor-1; leukocyte-associated immunoglobulin-like receptor 1; rLAIR1

LAIR1 (CD305) Antibodies

Target Information

Synonyms

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