NOXA Antibodies

Antibodies that detect NOXA can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, Flow Cytometry and ELISA. These antibodies target NOXA in Human, Mouse and Rat samples. Our NOXA polyclonal, monoclonal and recombinant... Antibodies that detect NOXA can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, Flow Cytometry and ELISA. These antibodies target NOXA in Human, Mouse and Rat samples. Our NOXA polyclonal, monoclonal and recombinant monoclonal antibodies are developed in... Antibodies that detect NOXA can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, Flow Cytometry and ELISA. These antibodies target NOXA in Human, Mouse and Rat samples. Our NOXA polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse and Goat. These antibodies have been verified by Cell treatment and Knockdown to confirm specificity to NOXA. Find the NOXA antibody that fits your needs. Choose from 1 of 12 NOXA antibodies, which have been validated in experiments with 18 publications and 34 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with... Antibodies that detect NOXA can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, Flow Cytometry and ELISA. These antibodies target NOXA in Human, Mouse and Rat samples. Our NOXA polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse and Goat. These antibodies have been verified by Cell treatment and Knockdown to confirm specificity to NOXA. Find the NOXA antibody that fits your needs. Choose from 1 of 12 NOXA antibodies, which have been validated in experiments with 18 publications and 34 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes including p53R2, p53AIP1, and PUMA. A new p53 target gene, Noxa, was recently identified, which encodes a protein belonging to the subfamily of BH3-only proapoptic proteins. Noxa and PUMA are both transcriptional targets of p53 and BH3-only proteins. X-ray irradiation increased p53-dependent Noxa mRNA and protein levels. Noxa, when ectopically expressed, interacted with anti-apoptotic Bcl-2 family members, resulting in the activation of caspase-9. Noxa, like PUMA, localized to mitochondria and induces apoptosis in response to p53. Noxa and PUMA may represent direct mediators of p53-induced apoptosis. Increased levels of p53 and its target gene Noxa was found in the impaired tumor development.

Synonyms

adult T cell leukemia-derived PMA-responsive; APR; Immediate-early-response protein APR; Noxa; Phorbol-12-myristate-13-acetate-induced protein 1; PMA-ind; PMA-induced protein 1; Pmaip1; Protein Noxa

NOXA Antibodies

Target Information

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