Perforin Antibodies

Antibodies that detect Perforin can be used in several scientific applications, including Immunohistochemistry, Western Blot, Flow Cytometry, ELISA and Peptide array. These antibodies target Perforin in Human, Mouse, Porcine and Rat samples. Our Perforin monoclonal, polyclonal and... Antibodies that detect Perforin can be used in several scientific applications, including Immunohistochemistry, Western Blot, Flow Cytometry, ELISA and Peptide array. These antibodies target Perforin in Human, Mouse, Porcine and Rat samples. Our Perforin monoclonal, polyclonal and recombinant monoclonal antibodies are developed in... Antibodies that detect Perforin can be used in several scientific applications, including Immunohistochemistry, Western Blot, Flow Cytometry, ELISA and Peptide array. These antibodies target Perforin in Human, Mouse, Porcine and Rat samples. Our Perforin monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rabbit and Rat. These antibodies have been verified by Cell treatment and Relative expression to confirm specificity to Perforin. Find the Perforin antibody that fits your needs. Choose from 1 of 51 Perforin antibodies, which have been validated in experiments with 287 publications and 184 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications.... Antibodies that detect Perforin can be used in several scientific applications, including Immunohistochemistry, Western Blot, Flow Cytometry, ELISA and Peptide array. These antibodies target Perforin in Human, Mouse, Porcine and Rat samples. Our Perforin monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rabbit and Rat. These antibodies have been verified by Cell treatment and Relative expression to confirm specificity to Perforin. Find the Perforin antibody that fits your needs. Choose from 1 of 51 Perforin antibodies, which have been validated in experiments with 287 publications and 184 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

Perforin is one of the major cytolytic proteins of cytolytic granules. Perforin is a cytolytic mediator and is stored in and released by cytoplasmic granules. Moreover, perforin is involved in immune defense against tumors and virus infections as mediated by cytotoxic lymphocytes. Perforin is a 555 amino acid protein with a 21 amino acid signal peptide, and has a molecular weight of 70 to 75 kD. Perforin is a pore forming protein with a mechanism of transmembrane channel formation similar to C9, and homology between perforin and C9 have been demonstrated. Studies show that perforin is expressed only in killer cell lines and not in helper T lymphocytes or other tumor cells tested. Perforin is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in the perforin gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants of perforin.

Synonyms

Cyta; Cytolysin; FLH2; HPLH2; lymphocyte pore forming protein; lymphocyte pore-forming protein; OMAK; OTTHUMP00000019759; P1; perforin 1; perforin 1 (pore forming protein); Perforin1; perforin-1; Pfn; PFN1; Pfp; PGFL; PIGF; PIGF-2; PLGF; pore forming protein; pore-forming protein; Prf1; Prf-1; PRF1 (pore forming protein 1); RATCYTA; RP11-710A11.3

Target Video

6320263338112

Perforin antibodies from Thermo Fisher Scientific

https://cf-images.us-east-1.prod.boltdns.net/v1/static/3663210762001/253d7a43-fd66-4863-9d30-1b4574f3a548/aae9a801-bf5c-4003-8e27-e17d0c4bf0c0/160x90/match/image.jpg

Learn more about Perforin primary antibodies that can be used in Immunohistochemistry, Western Blot, Flow Cytometry and ELISA in Human, Mouse, Pig and Rat samples.

perforin

PT0M32S

2023-02-12T17:00:23.446Z

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Perforin Antibodies

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