Syntenin 1 Antibodies

Target Information

The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms

MDA9; MDA-9; melanoma differentiation associated protein-9; melanoma differentiation-associated protein 9; Pro-TGF-alpha cytoplasmic domain-interacting protein 18; sb:eu862; Scaffold protein Pbp1; sdcbp; si:dkey-235k4.1; ST1; SYCL; syndecan binding protein; syndecan binding protein (syntenin); syndecan interacting protein; syndecan-binding protein 1; syntenin; syntenin-1; syntenin-b; TACIP18