Securin Antibodies

Antibodies that detect Securin can be used in several scientific applications, including Western Blot, Immunocytochemistry, ELISA, Immunohistochemistry and Flow Cytometry. These antibodies target Securin in Human, Mouse and Rat samples. Our Securin monoclonal, polyclonal and recombinant... Antibodies that detect Securin can be used in several scientific applications, including Western Blot, Immunocytochemistry, ELISA, Immunohistochemistry and Flow Cytometry. These antibodies target Securin in Human, Mouse and Rat samples. Our Securin monoclonal, polyclonal and recombinant monoclonal antibodies are developed in... Antibodies that detect Securin can be used in several scientific applications, including Western Blot, Immunocytochemistry, ELISA, Immunohistochemistry and Flow Cytometry. These antibodies target Securin in Human, Mouse and Rat samples. Our Securin monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rabbit and Goat. These antibodies have been verified by Knockdown and Cell treatment to confirm specificity to Securin. Find the Securin antibody that fits your needs. Choose from 1 of 20 Securin antibodies, which have been validated in experiments with 76 publications and 83 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with... Antibodies that detect Securin can be used in several scientific applications, including Western Blot, Immunocytochemistry, ELISA, Immunohistochemistry and Flow Cytometry. These antibodies target Securin in Human, Mouse and Rat samples. Our Securin monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rabbit and Goat. These antibodies have been verified by Knockdown and Cell treatment to confirm specificity to Securin. Find the Securin antibody that fits your needs. Choose from 1 of 20 Securin antibodies, which have been validated in experiments with 76 publications and 83 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) substrate that associates with a separin until activation of the APC. The gene product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. The gene product contains 2 PXXP motifs, which are required for its transforming and tumorigenic activities, as well as for its stimulation of basic fibroblast growth factor expression. It also contains a destruction box (D box) that is required for its degradation by the APC. The acidic C-terminal region of the encoded protein can act as a transactivation domain. The gene product is mainly a cytosolic protein, although it partially localizes in the nucleus.

Synonyms

AW555095; C87862; EAP1; Esp1-associated protein; ESP1-associated protein 1; HPTTG; MGC126883; MGC138276; Pituitary tumor transforming; pituitary tumor-transforming 1; pituitary tumor-transforming gene 1; pituitary tumor-transforming gene 1 protein; PTTG; PTTG1; Pttg3; Securin; Tumor-transforming protein 1; TUTR1

Securin Antibodies

Target Information

Synonyms

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