SHP-1 Antibodies

Antibodies that detect SHP-1 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, Flow Cytometry and Immunoprecipitation. These antibodies target SHP-1 in Human, Mouse and Rat samples. Our SHP-1 polyclonal, monoclonal and... Antibodies that detect SHP-1 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, Flow Cytometry and Immunoprecipitation. These antibodies target SHP-1 in Human, Mouse and Rat samples. Our SHP-1 polyclonal, monoclonal and recombinant monoclonal antibodies... Antibodies that detect SHP-1 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, Flow Cytometry and Immunoprecipitation. These antibodies target SHP-1 in Human, Mouse and Rat samples. Our SHP-1 polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse and Goat. These antibodies have been verified by Relative expression to confirm specificity to SHP-1. Find the SHP-1 antibody that fits your needs. Choose from 1 of 46 SHP-1 antibodies, which have been validated in experiments with 18 publications and 105 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications.... Antibodies that detect SHP-1 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, Flow Cytometry and Immunoprecipitation. These antibodies target SHP-1 in Human, Mouse and Rat samples. Our SHP-1 polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse and Goat. These antibodies have been verified by Relative expression to confirm specificity to SHP-1. Find the SHP-1 antibody that fits your needs. Choose from 1 of 46 SHP-1 antibodies, which have been validated in experiments with 18 publications and 105 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

SHP-1 (PTPN6) is a non-receptor protein tyrosine phosphatase that is expressed primarily in hematopoietic cells. The enzyme is composed of two SH2 domains, a tyrosine phosphatase catalytic domain, and a carboxy-terminal regulatory domain. SHP-1 removes phosphates from target proteins to downregulate several tyrosine kinase-regulated pathways. In hematopoietic cells, the amino-terminal SH2 domain of SHP-1 binds to tyrosine phosphorylated erythropoietin receptors (EpoR) to negatively regulate hematopoietic growth. Overexpression of SHP-1 in epithelial cells results in dephosphorylation of the Ros receptor tyrosine kinase and subsequent downregulation of Ros-dependent cell proliferation and transformation. Following ligand binding in myeloid cells, SHP-1 associates with the IL-3R beta chain and downregulates IL-3-induced tyrosine phosphorylation and cell proliferation.

Synonyms

70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; Hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; Ptpn6; PTPTY-42; SH2 phosphatase 1; SHP1; SHP-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6

Target Video

6320271410112

SHP-1 antibodies from Thermo Fisher Scientific

https://cf-images.us-east-1.prod.boltdns.net/v1/static/3663210762001/1c5d4ca4-50e2-4333-a250-ded92ae81eed/79364012-1890-41b0-acc2-fc06fc4d143f/320x180/match/image.jpg

Learn more about SHP-1 primary antibodies that can be used in Western Blot, Immunocytochemistry, Immunohistochemistry and Flow Cytometry in Human, Mouse and Rat samples.

shp-1

PT0M37S

2023-02-12T18:19:40.267Z

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SHP-1 Antibodies

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